227201-49-2Relevant academic research and scientific papers
Diastereoselective synthesis of atropisomers containing two non-biaryl stereogenic axes: Stereochemical relay through stereogenic centres in dihydrostilbene-2,2′-dicarboxamides
Clayden, Jonathan,Westlund, Neil,Frampton, Christopher S.,Helliwell, Madeleine
, p. 455 - 461 (2006)
Addition of laterally lithiated tertiary aromatic amides to benzaldimines controls the formation of a new stereogenic centre adjacent to the benzaldimine aromatic ring. Drawing on the fact that such amino-substituted stereogenic centres may themselves con
Synthesis of atropisomeric diamides with remotely related stereogenic axes by stereoselective additions to imines
Clayden, Jonathan,Westlund, Neil,Wilson, Francis X.
, p. 3331 - 3334 (2007/10/03)
Atroposelective addition of axially chiral laterally lithiated 2-alkyl- 1-naphthamides to 6-substituted 2-(N-methylformimino)benzamides leads, after equilibration of the new stereogenic axis to its more stable conformation, to single atropisomeric diaster
