22730-63-8Relevant academic research and scientific papers
Efficient, Solvent-Free, Multicomponent Method for Organic-Base-Catalyzed Synthesis of β-Phosphonomalonates
Kalla, Reddi Mohan Naidu,Park, Huiju,Lee, Hye Ri,Suh, Hongsuk,Kim, Il
supporting information, p. 691 - 697 (2015/11/18)
An efficient, one-pot, di-n-butylamine-catalyzed, three-component synthesis of β-phosphonomalonates has been developed. A wide range of substrates, including aromatic and fused aromatic aldehydes, were condensed with enolizable C-H activated compounds and dialkylphosphites to give the desired products in excellent yields. This method provides an eco-friendly alternative approach to rapid construction of a diversity-oriented library of β-phosphonomalonates.
Novel ionic tagged amine anchored on magnetic nanoparticles: An efficient and magnetically recyclable catalyst for Phospha-Michael addition
Li, Zhifeng,Ni, Yuxiang,Qiu, Fangli,Ying, Anguo,Xu, Songlin,Wang, Yunlong
, p. 1810 - 1818 (2015/02/05)
Ionic tagged propyl amine immobilized on magnetic nanoparticles (MNPs) was synthesized and fully characterized. The novel catalyst (MNPs@PA-IL) was applied in phospha-Michael addition and gave the desired β-phosphonomalonates in good yields. The MNPs supported catalyst with ionic tag could be readily recovered from the reaction mixture using an external magnet. Compared with ionic-free counterpart (MNPs@PA), MNPs@PA-IL present better catalytic activity. The proposed mechanism regarding the MNPs@PA-IL catalyzed phospha-Michael reaction was also discussed.
