22741-15-7Relevant academic research and scientific papers
Synthesis of α,α,β,β-Tetrasubstituted β-Lactones from Ketones, Ethyl α-Bromoisobutyrate, and Indium or Zinc. Factors Influencing the β-Lactone Formation in the Electrochemical and the Classical Procedure of the Reformatsky Reaction
Schick, Hans,Ludwig, Ralf,Schwarz, Karl-Heinz,Kleiner, Katharina,Kunath, Annamarie
, p. 3161 - 3164 (2007/10/02)
An efficient synthesis of α,α,β,β-tetrasubstituted β-lactones is achieved by an electrochemically supported Reformatsky reaction of aliphatic and aromatic ketones with ethyl α-bromoisobutyrate at a sacrificial indium anode.Under these conditions, in most
