20279-29-2

Basic information

• Product Name: ISOBUTYRIC ACID PHENYL ESTER
• Synonyms: Phenyl 2-methylpropanoate;phenyl 2-methylpropionate;ISOBUTYRIC ACID PHENYL ESTER;PHENYL ISOBUTYRATE
• CAS NO: 20279-29-2
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 20279-29-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 110 °C / 22mmHg
• Flash Point: 88.6°C
• Appearance: /
• Density: 1.01
• Vapor Pressure: 0.0931mmHg at 25°C
• Refractive Index: 1.4850 to 1.4880
• CAS DataBase Reference: ISOBUTYRIC ACID PHENYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: ISOBUTYRIC ACID PHENYL ESTER(20279-29-2)
• EPA Substance Registry System: ISOBUTYRIC ACID PHENYL ESTER(20279-29-2)

Safety Data

• Hazardous Substances Data: 20279-29-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 3365, 1983 DOI: 10.1016/S0040-4039(00)86271-1

InChI:InChI=1/C10H12O2/c1-8(2)10(11)12-9-6-4-3-5-7-9/h3-8H,1-2H3

Upstream product

• 359-48-8 trifluoroacetyl peroxide 
• 107-06-2 1,2-dichloro-ethane 
• 75-05-8 acetonitrile 
• 611-70-1 phenyl isopropyl ketone 
• 75-09-2 dichloromethane 
• 97-72-3 2-Methylpropionic anhydride 
• 108-95-2 phenol 
• 940391-44-6 N-phenyl-N-tosylisobutyramide 
• 98-80-6 phenylboronic acid 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 79-31-2 isobutyric Acid 
• 2177-70-0 phenyl methacrylate 
• 201230-82-2 carbon monoxide 
• 16883-61-7 trimethylsilyl isobutyrate 

Downstream Products

• 34917-91-4 4-hydroxyisobutyrophenone 
• 6640-69-3 1-(2-hydroxyphenyl)-2-methylpropan-1-one 
• 155397-18-5 2-methyl-1,1-bispropan-1-ol 
• 4195-16-8 4-nitrophenyl isobutyrate 
• 53305-63-8 2-nitrophenyl 2-methylpropanoate 
• 1626437-21-5 phenyl 2,2-dimethyl-3-phenyl-3-(trimethylsiloxy)butanoate 
• 1626437-22-6 phenyl 2,2-dimethyl-3-(2-naphthyl)-3-(trimethylsiloxy)butanoate 
• 1626437-23-7 phenyl 2,2-dimethyl-3-(2-naphthyl)-3-(trimethylsiloxy)but-3-enoate 
• 1626437-24-8 phenyl 3-butyl-2,2-dimethyl-3-(trimethylsiloxy)heptanoate 
• 6642-37-1 N-(4-methoxyphenyl)isobutyramide 
• 1309610-52-3 C₂₁H₂₅NO₂ 
• 120615-54-5 trimethyl((2-methyl-1-phenoxyprop-1-en-1-yl)oxy)silane 
• 1058629-01-8 C₁₁H₁₁BrO₂ 
• 72486-22-7 4-Methyl-1-phenylpenta-1,3-diene 

Relevant articles and documents

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Palladium-Catalyzed Aerobic Oxidative Coupling of Amides with Arylboronic Acids by Cooperative Catalysis

The first fluoride and palladium co-catalyzed conversion of amide to ester through an aerobic oxidative coupling pathway is reported. This new approach presents a practical process that employs easily available oxygen and commercially available arylboronic acids as coupling partners, uses a wide range of N- tosylamides, and proceeds under mild reaction conditions. This protocol demonstrates broad functional group tolerance, and provides an alternative option to synthesize esters from N-tosylamides which obtained by simply N-functionalization of secondary amides.

The insertion of arynes into the O-H bond of aliphatic carboxylic acids

The insertion of arynes into the O-H bond of aliphatic carboxylic acids promoted by sodium carboxylates is described. The reactions led to the formation of aryl carboxylates in good yields with good chemoselectivities under mild conditions.