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227449-05-0

5-Pyrimidinecarboxylic acid, 2-chloro-4-[(4-methylphenyl)amino]-, ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 227449-05-0 Structure

  • Basic information

    1. Product Name: 5-Pyrimidinecarboxylic acid, 2-chloro-4-[(4-methylphenyl)amino]-, ethyl ester
    2. Synonyms:
    3. CAS NO:227449-05-0
    4. Molecular Formula: C14H14ClN3O2
    5. Molecular Weight: 291.737
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 227449-05-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 2-chloro-4-[(4-methylphenyl)amino]-, ethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 2-chloro-4-[(4-methylphenyl)amino]-, ethyl ester(227449-05-0)
    11. EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 2-chloro-4-[(4-methylphenyl)amino]-, ethyl ester(227449-05-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 227449-05-0(Hazardous Substances Data)

227449-05-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 227449-05-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,4,4 and 9 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 227449-05:
(8*2)+(7*2)+(6*7)+(5*4)+(4*4)+(3*9)+(2*0)+(1*5)=140
140 % 10 = 0
So 227449-05-0 is a valid CAS Registry Number.

227449-05-0Relevant articles and documents

SELECTIVE KINASE INHIBITORS

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Paragraph 0512; 0513, (2013/06/06)

Provided are pyrimidine compounds for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibition Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.

Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives

Hisamichi, Hiroyuki,Naito, Ryo,Toyoshima, Akira,Kawano, Noriyuki,Ichikawa, Atsushi,Orita, Akiko,Orita, Masaya,Hamada, Noritaka,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi

, p. 4936 - 4951 (2007/10/03)

Spleen tyrosine kinase (Syk) is a non-receptor-type tyrosine kinase which mediates diverse responses in haematopoietic cells. Therefore, Syk is an attractive therapeutic target, and in a study of Syk inhibitors as potentially new therapeutic agents, we di

Pyrimidine-5-carboxamide derivatives

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, (2008/06/13)

Pyrimidine-5-carboxamide derivatives represented by a general formula (I) or salts thereof [wherein each symbol has the following meaning; X: O, S, NR1, CO, NR1CO, CONR1, C═N—OR1or a bond, Y: a lower alkylene gr

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