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Curcumin β-D-Glucuronide is a metabolite of Curcumin, a natural phenolic compound derived from the rhizomes of the plant Curcuma longa, commonly known as turmeric. It is characterized by its dark orange solid appearance and is formed in hepatic tissue and portal blood as a result of the metabolism of Curcumin.

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  • 227466-72-0 Structure
  • Basic information

    1. Product Name: Curcumin β-D-Glucuronide
    2. Synonyms: Curcumin β-D-Glucuronide;4-[(1E,6E)-7-(4-Hydroxy-3-Methoxyphenyl)-3,5-dioxo-1,6-heptadien-1-yl]-2-Methoxyphenyl β-D-Glucopyranosiduronic Acid;Curcumin-4-O-beta-D-glucuronide min. 85%
    3. CAS NO:227466-72-0
    4. Molecular Formula: C27H28O12
    5. Molecular Weight: 544.50402
    6. EINECS: N/A
    7. Product Categories: Aromatics;Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 227466-72-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 838.7±65.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.470±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 2.78±0.70(Predicted)
    10. CAS DataBase Reference: Curcumin β-D-Glucuronide(CAS DataBase Reference)
    11. NIST Chemistry Reference: Curcumin β-D-Glucuronide(227466-72-0)
    12. EPA Substance Registry System: Curcumin β-D-Glucuronide(227466-72-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 227466-72-0(Hazardous Substances Data)

227466-72-0 Usage

Uses

Used in Pharmaceutical Industry:
Curcumin β-D-Glucuronide is used as a pharmaceutical agent for its potential therapeutic properties. As a metabolite of Curcumin, it may contribute to the overall health benefits associated with Curcumin, such as its anti-inflammatory, antioxidant, and anticancer activities.
Used in Research Applications:
Curcumin β-D-Glucuronide is used as a research compound to study the metabolism and bioavailability of Curcumin. Understanding its role in the body can help researchers develop more effective formulations and delivery systems for Curcumin and its derivatives, potentially enhancing their therapeutic effects.
Used in Analytical Chemistry:
Curcumin β-D-Glucuronide can be used as a reference standard or analytical tool in the development and validation of analytical methods for the detection and quantification of Curcumin and its metabolites in biological samples, such as blood, urine, or tissue extracts. This can be important for assessing the bioavailability, pharmacokinetics, and safety of Curcumin-based products.

Check Digit Verification of cas no

The CAS Registry Mumber 227466-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,4,6 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 227466-72:
(8*2)+(7*2)+(6*7)+(5*4)+(4*6)+(3*6)+(2*7)+(1*2)=150
150 % 10 = 0
So 227466-72-0 is a valid CAS Registry Number.

227466-72-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]-2-methoxyphenoxy]oxane-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names 4-[(1E,6E)-7-(4-Hydroxy-3-methoxyphenyl)-3,5-dioxo-1,6-heptadien-1-yl]-2-methoxyphenyl |A-D-Glucopyranosiduronic Acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:227466-72-0 SDS

227466-72-0Downstream Products

227466-72-0Relevant articles and documents

DRUG COMPOSITION FOR PARENTERAL ADMINISTRATION

-

, (2019/05/16)

Provided is a curcumin pharmaceutical preparation that is highly water soluble, can maintain the concentration of free curcumin in the blood sufficiently high by being administered parenterally, can effectively obtain a pharmacological action of curcumin,

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