22755-09-5

Basic information

• Product Name: N-phenyl hydroxylamine hydrochloride
• Synonyms: N-phenyl hydroxylamine hydrochloride
• CAS NO: 22755-09-5
• Molecular Weight: 145.589
• Mol File: 22755-09-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-phenyl hydroxylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl hydroxylamine hydrochloride(22755-09-5)
• EPA Substance Registry System: N-phenyl hydroxylamine hydrochloride(22755-09-5)

Safety Data

• Hazardous Substances Data: 22755-09-5(Hazardous Substances Data)

Upstream product

• 304-88-1 N-phenylbenzohydroxamic acid 

Downstream Products

• 6903-41-9 Iminokohlensaeure-<3-chlor-phenylester>-phenylhydroxylamid 
• 19393-60-3 N-phenyl-salicylohydroxamic acid 
• 351464-82-9 N-Phenoxyundecanamide 
• 4645-72-1 N-hydroxy-N-phenyl-carbamic acid phenyl ester 
• 825645-30-5 E-C-(2-butyl-4-chloro-1H-imidazol-5-yl)-N-phenylnitrone 
• 1156491-57-4 (1R*,4S*)-2-phenyl-1,2,4,5-tetrahydro-1,4-methano[1,2,5]oxadiazepino[5,4-a]benzimidazole 
• 20147-41-5 N-(pyridin-3-ylmethylidene)-N-phenylaminoxide 

Relevant articles and documents

Effect of solvents on the kinetics and mechanism of the acidic and alkaline hydrolysis of hydroxamic acids

The acid catalyzed hydrolysis of N-phenylbenzohydroxamic acid (PBHA) C6H5C(=0)N(OH)C6H5 has been studied in aq. dioxane, acetone, dimethylsulphoxide, dimethylformamide, methanol, ethanol and 2-propanol mixtures. Dioxane and methanol have a rate enhancing effect but DMF, acetone, ethanol and 2-propanol exert a rate decreasing effect. In DMSO an increase is followed by a decrease i.e. a rate maximum is observed. An attempt has also been made to study the alkaline hydrolysis of PBHA and two of its derivatives (X-C6H4C(=0)N(OH)C6H5; X=4-NO2, 4-Cl) in aq. dioxane. In all case the pseudo first order rate constant increase with increasing dioxane content. The activation parameters ΔH(+), Δ(+), and ΔGH(+) have been calculated. An attempt has been made to correlate rate data for acidic hydrolysis in terms of solvatochromic parameters and linear free energy relationships.