22763-69-5

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Pyrrolidinoethyl)piperazine is used as an intermediate for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the creation of a wide range of medications, making it an essential component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(2-Pyrrolidinoethyl)piperazine is used as a key raw material in the production of various agrochemical products. Its properties contribute to the effectiveness of these products, enhancing their performance in agricultural applications.
Used in Dye Industry:
1-(2-Pyrrolidinoethyl)piperazine is also utilized as a vital component in the dye industry. Its chemical properties make it suitable for the creation of a diverse range of dyes, contributing to the vibrancy and variety of colors available in the market.

InChI:InChI=1/C10H21N3/c1-2-6-12(5-1)9-10-13-7-3-11-4-8-13/h11H,1-10H2/p+3

Upstream product

• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 7250-67-1 1-(2-chloroethyl)pyrrolidine hydrochloride 
• 77279-24-4 tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate 
• 208167-83-3 tert-butyl 4-(2-chloroethyl)tetrahydro-1(2H)-pyrazinecarboxylate 
• 1453097-93-2 tert-butyl 4-(2-(pyrrolidine-1-yl)ethyl)piperazine-1-carboxylate 

Downstream Products

• 444661-98-7 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-{[4-(2-pyrrolidin-1-ylethyl) piperazin-1-yl]sulfonyl}-3,4-dihydroquinazolin-2(1H)-one 
• 1032611-69-0 4-[2-(2,4-dichlorophenoxy)phenylsulfamoyl]-N-{2-oxo-2-[4-(2-pyrrolidin-1-ylethyl)piperazin-1-yl]ethyl}benzamide 
• 939977-52-3 5-(2,4-dichlorobenzylamino)-3-[4-(2-pyrrolidin-1-ylethyl)piperazin-1-yl]-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 939977-51-2 cyclopropanecarboxylic acid {5-(2,4-dichlorobenzylamino)-3-[4-(2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-[1,2,4]triazin-6-ylmethyl}-amide 

Relevant academic research and scientific papers

3-PHENYLSULPHONYL-QUINOLINE DERIVATIVES AS AGENTS FOR TREATING PATHOGENIC BLOOD VESSELS DISORDERS

The disclosure provides compounds, and compositions, including pharmaceutical compositions, kits that include the compounds, and methods of using (or administering) and making the compounds. The disclosure further provides compounds or compositions thereof for use in a method of modulating PLXDC1 (TEM7) and/or PLXDC2 or killing pathogenic blood vessles. The disclosure further provides compounds or compositions thereof for use in a method of treating a disease, disorder, or condition that is mediated, at least in part, by PEDF receptors or by angiogenesis.

A anthraquinone and thiazole compounds, its preparation method and use thereof

The invention relates to a compound which takes 5,7-dihydroxyanthraquinone [2,1-d]thiazole as a mother nucleus, which has a following general formula, and relates to a preparation method and an application of the compound in an antitumor drug. The compound takes a traditional natural product rheinic acid as an initial raw material, and a series of compound with high antineoplastic activity is synthesized through mild reaction condition. The antitumor activity in vitro of the preferable compound is stronger by more than 30 times by comparing with rheinic acid.

Natural product-based design, synthesis and biological evaluation of anthra[2,1-d]thiazole-6,11-dione derivatives from rhein as novel antitumour agents

Two series of novel 2-substituted 5,7-dihydroxyanthra[2,1-d]thiazole-6,11- dione derivatives from natural rhein were designed, synthesized and evaluated for their antitumour activities against human cancer cell lines A549 and HeLa in vitro.

Optically active 1,4-dihydropyridine compounds as bradykinin antagonists

This invention provides a compound of the formula (I): and its pharmaceutically acceptable salts, wherein A1 and A2 are each halo; R1 and R2 are independently C1-4 alkyl; R3 is substituted or unsubstituted, phenyl or naphthyl; Y is heterocyclic group sele