22768-05-4Relevant academic research and scientific papers
Sodium borohydride and vinyl triflates of α-keto esters: A new combination toward monoalkylated 1,2-diols
Dalla, Vincent,Decroix, Bernard
, p. 1657 - 1660 (2002)
NaBH4 converts a range of methyl 2-trifluoromethanesulfonyloxy 3-substituted propenoates to the corresponding monoalkylated 1,2-diols smoothly with total regiocontrol.
(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER
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, (2020/07/15)
The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.
Pyrrolidine and thiazolidine derivatives, their preparation and medicaments containing them
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, (2008/06/13)
This invention relates to compositions of formula: STR1 and their salts, their preparation and the medicaments containing them.
SELECTIVE C-C BOND HYDROGENATION IN UNSATURATED NITRO COMPOUNDS IN THE PRESENCE OF THE RhCl3-ALIQUAT 336 CATALYST SYSTEM
Amer, Ibrahim,Bravdo, Tamar,Blum, Jochanan,Vollhardt, K. Peter C.
, p. 1321 - 1322 (2007/10/02)
The ion pair formed from aqueous rhodium trichloride and Aliquat 336 catalyzes the selective hydrogenation of olefinic bonds of a variety of unsaturated nitro compounds in a two liquid phase system at 30 deg C.Nitrobenzene gives, under these conditions, a mixture of aniline and nitrocyclohexane.
