227796-00-1

Basic information

• Product Name: 7,16-bis(5-chloro-2-hydroxy-3-trifluoroacetamidobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane
• Synonyms: 7,16-bis(5-chloro-2-hydroxy-3-trifluoroacetamidobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane
• CAS NO: 227796-00-1
• Molecular Weight: 765.534
• Mol File: 227796-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7,16-bis(5-chloro-2-hydroxy-3-trifluoroacetamidobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane(CAS DataBase Reference)
• NIST Chemistry Reference: 7,16-bis(5-chloro-2-hydroxy-3-trifluoroacetamidobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane(227796-00-1)
• EPA Substance Registry System: 7,16-bis(5-chloro-2-hydroxy-3-trifluoroacetamidobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane(227796-00-1)

Safety Data

• Hazardous Substances Data: 227796-00-1(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 93416-35-4 N-(5-chloro-2-hydroxyphenyl)trifluoroacetamide 
• 23978-55-4 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane 
• 95-85-2 2-hydroxy-5-chloro-aniline 

Relevant articles and documents

Diaza-18-Crown-6 Ligands Containing Two Aminophenol Side Arms: New Heterobinuclear Metal Ion Receptors

Three diaza-18-crown-6 ligands substituted with two aminophenol side arms were synthesized as possible heterobinuclear metal ion receptors. Bis(p-aminophenol)-substituted diaza-18-crown-6 ligand (13) was prepared by treating the diazacrown with α-bromo-4-nitro-o-cresol in the presence of N,N-diisopropylethylamine followed by reduction of the nitro groups. Bis(o-aminophenol)-substituted diaza-18-crown-6 ligands (11 and 12) were prepared in two steps by the aminomethylation of either an o-nitrophenol or o-(trifluoroacetamido)phenol followed by reduction of the nitro groups or hydrolysis of the trifluoroacetamide groups. All new bisphenol-armed diazacrown ligands were purified by ultrasonication in MeOH followed by filtration and drying. Interaction of the ligands with Na+, K+, Ag+, and Cu2+ was evaluated by a calorimetric titration technique at 25°C in MeOH. The complexes of Ag+ and Cu2+ are much more stable than those of Na+ and K+. Heterobinuclear complexes were observed for 11-Cu2+ - Na+ and 12-Cu2+-Na+ but not for 13-Cu2+-Na+ or for 12-Cu2+-Ag+.