2278-10-6 Usage
Uses
Used in Food Industry:
(3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one is used as a coloring agent for its yellow-orange hue, enhancing the visual appeal of various food products.
Used in Cosmetic Industry:
In cosmetics, (3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one serves as a natural coloring agent, providing a vibrant shade to products while also offering potential health benefits due to its antioxidant properties.
Used in Pharmaceutical Industry:
(3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one is used as a potential therapeutic agent for its antioxidant and anti-inflammatory properties, with studies suggesting its effectiveness against diseases such as cancer, diabetes, arthritis, and Alzheimer's disease.
Used as a Dietary Supplement:
Due to its safety for consumption in small amounts and potential health benefits, (3Z,5E)-4-hydroxy-6-phenylhexa-3,5-dien-2-one is often used as a dietary supplement to support overall health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 2278-10-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,7 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2278-10:
(6*2)+(5*2)+(4*7)+(3*8)+(2*1)+(1*0)=76
76 % 10 = 6
So 2278-10-6 is a valid CAS Registry Number.
2278-10-6Relevant academic research and scientific papers
2-Hydroxycurcuminoid induces apoptosis of human tumor cells through the reactive oxygen species-mitochondria pathway
Han, Young-Min,Shin, Dae-Seop,Lee, Yu-Jin,Ismail, Ismail Ahmed,Hong, Su-Hyung,Han, Dong Cho,Kwon, Byoung-Mog
scheme or table, p. 747 - 751 (2011/03/18)
2-Hydroxycinnamaldehyde (HCA) and curcumin have been reported to have antitumor effects against various human tumor cells in vitro and in vivo by generation of ROS. Aldehyde-free HCA analogs were synthesized based on the structure of curcumin, which we have called 2-hydroxycurcuminoids. The hydroxyl group of curcuminoids enhances the ability to generate ROS. 2-Hydroxycurcuminoid (HCC-7) strongly inhibited the growth of SW620 colon tumor cells with a GI 50 value of 7 μM, while the parent compounds, HCA and curcumin, displayed GI50 values of 12 and 30 μM, respectively. HCC-7 was found to induce apoptosis through the reactive oxygen species-mitochondria pathway and cell cycle arrest at G2/M phase.
