227804-35-5

Usage

Uses

Used in Pharmaceutical Industry:
(3,4-dimethoxyphenyl)-N-hydroxymethanamine is used as a precursor in organic synthesis for the production of various pharmaceuticals. Its unique structure and reactivity make it a valuable building block for the development of new drug candidates.
Used in Agrochemical Industry:
(3,4-dimethoxyphenyl)-N-hydroxymethanamine is also used as a precursor in the synthesis of agrochemicals, contributing to the development of effective and innovative products for agricultural applications.
Used in Medicinal Chemistry:
(3,4-dimethoxyphenyl)-N-hydroxymethanamine has potential applications in the field of medicinal chemistry as a building block for the development of new drug candidates. Its versatile chemical properties and reactivity make it a promising candidate for the synthesis of a wide range of valuable products.

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 2169-98-4 3,4-Dimethoxy-benzaldehyde oxime 

Downstream Products

• 227804-41-3 C₁₄H₂₁NO₃ 
• 1417406-92-8 C₂₁H₂₃NO₇ 
• 227804-47-9 4-[(3,4-dimethoxy-benzyl)-hydroxy-amino]-6-methyl-hept-2-ynoic acid tert-butyl ester 

Relevant academic research and scientific papers

One-pot synthesis of dihydrobenzisoxazoles from hydroxylamines, acetylenedicarboxylates, and arynes via in situ generation of nitrones

Aryne [3 + 2] cycloaddition with nitrones generated in situ from the addition of hydroxylamines to acetylenedicarboxylates affords moderate to good yields of dihydrobenzisoxazoles. This reaction extends the current scope of aryne cycloaddition to include in situ generated nitrones and produces functionalized dihydrobenzisoxazoles with a quaternary center.

Phase-transfer catalysis for the synthesis of hydroxylamines from oximes using benzyltriethylammonium borohydride in methanol and under solid-phase conditions

Effective phase-transfer catalysis methodologies for the reduction of oximes to hydroxylamines by a selective and versatile reducing agent, benzyltriethylammonium borohydride (BTEABH), in methanol and under solid-phase conditions are presented.

NOVEL DIAZENIUMDIOLATE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF

TITLE: The present invention relates to the compounds of the formula (I) to the process for the preparation of them and their therapeutic use, especially their use as antioxidants, as NO generators, and as inhibitors of smooth muscle cell proliferation.

Synthesis of Z-α,β-ethylenic N-boc-γ-amino esters from nitrones

The reduction of γ-N-hydroxylamino-α,β-acetylenic esters bearing a methoxy-substituted benzyl group on the nitrogen atom by zinc in a MeOH/AcOH mixture leads stereoselectively to Z-γ-amino-α,β-ethylenic esters.