227946-96-5

Upstream product

• 78-84-2 isobutyraldehyde 
• 254114-95-9 (para-bromophenyl)diethylphosphonoacetate 

Downstream Products

• 227946-97-6 (2R,3S)-(para-bromophenyl)-2-benzylcarbamate-3-hydroxy-4-methylpentanoate 
• 227946-98-7 (4S,5S)-4-((E)-(1S,2S)-1-Hydroxy-5-methoxycarbonyl-2-methyl-pent-3-enyl)-5-isopropyl-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 141970-53-8 (2R,3S)-2-Benzyloxycarbonylamino-3-hydroxy-4-methyl-pentanoic acid methyl ester 
• 154226-60-5 omuralide 
• 148843-21-4 (4S,5S)-4-((1S,2R)-2-Carboxy-1-hydroxy-propyl)-5-isopropyl-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 148843-18-9 (4S,5S)-4-Hydroxymethyl-5-isopropyl-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 148843-19-0 (4R,5S)-4-Formyl-5-isopropyl-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 148906-20-1 (4R,5S)-5-isopropyl-2-phenyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester 
• 133343-34-7 Lactacystin 
• 145451-97-4 (3R,4S,5R,1'S)-4-hydroxy-5-(1'-hydroxy-2'-methylpropyl)-3-methylpyrrolidin-2-one-5-carboxylic acid 
• 87421-19-0 (2R)-2-Amino-3-hydroxy-4-methylpentansaeure-methylester 

Relevant academic research and scientific papers

Reversal of Regioselection in the Sharpless Asymmetric Aminohydroxylation of Aryl Ester Substrates

(Matrix Presented) The asymmetric synthesis of β-hydroxy-α-amino acids is reported which relies on the use of α,β-unsaturated aryl ester substrates and the dihydroquinyl alkaloid ligand system (DHQ)2-AQN to control the regio- and enantioselectivity of the asymmetric aminohydroxylation (AA) process. α,β-Unsaturated ester substrates of type 1 have a significant effect on the substrate - ligand recognition event which results in a reversal of regioselectivity in the AA reaction.