227963-57-7

Basic information

• Product Name: ETHYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE
• Synonyms: 3-(6-AMINO-PYRIDIN-3-YL)-ACRYLIC ACID ETHYL ESTER;ETHYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE;Ethyl 3-(2-amino-5-bromo-3-pyridyl)acrylate;(E)-ethyl 3-(2-amino-5-bromopyridin-3-yl)acrylate;(E)-3-(6-Aminopyridin-3-yl)-2-propenoic acid ethyl ester;ethyl 3-(6-aminopyridine-3-yl)acrylate;Ethyl(2-aMino-5-broMo-3-pyridyl)acrylate;(E)-3-(2-aMino-5-broMopyridin-3-yl)acrylate
• CAS NO: 227963-57-7
• Molecular Formula: C₁₀H₁₂N₂O₂
• Molecular Weight: 192.22
• EINECS: 256-495-9
• Mol File: 227963-57-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 142.8-142.9°C
• Boiling Point: 356.6 °C at 760 mmHg
• Flash Point: 169.4 °C
• Appearance: /
• Density: 1.183
• Vapor Pressure: 2.9E-05mmHg at 25°C
• Refractive Index: 1.599
• PKA: 5.10±0.13(Predicted)
• CAS DataBase Reference: ETHYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE(227963-57-7)
• EPA Substance Registry System: ETHYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE(227963-57-7)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 227963-57-7(Hazardous Substances Data)

Usage

General Description

ETHYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE is a chemical compound with the molecular formula C11H11BrN2O2. It is a yellow to brown solid with a molecular weight of 276.12 g/mol. ETHYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE is commonly used in the synthesis of organic compounds and pharmaceuticals due to its unique structure and reactivity. It is also known for its potential biological activity and is being studied for its potential use in various applications in the fields of medicine and biotechnology. However, its specific properties and uses may vary depending on the context in which it is being employed.

InChI:InChI=1/C10H12N2O2/c1-2-14-10(13)6-4-8-3-5-9(11)12-7-8/h3-7H,2H2,1H3,(H2,11,12)/b6-4+

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
• 140-88-5 ethyl acrylate 
• 69879-22-7 6-amino-3-pyridinecarbaldehyde 

Downstream Products

• 910823-54-0 3-[3-(benzo[1,3]dioxol-5-ylamino)-2-phenethyl-imidazo[1,2-a]pyridin-6-yl]-acrylic acid ethyl ester 

Relevant articles and documents

Imidazolylamide derivative

The present invention pertains to an imidazolylamide derivative represented by formula (1) that exhibits an exceptional suppressive effect on cancer cell sphere formation ability and that is useful as an antitumor agent that can be administered orally, or a pharmacologically acceptable salt thereof. [In the formula, ring Q1 represents a C6-10 aryl group or the like; m represents 0, 1, 2, 3, 4, or 5; R3, independently when multiple, represent(s) a halogen atom or the like; R1 and R2 independently represent a hydrogen atom or the like; W1 represents a C1-4 alkylene group (said group may be substituted by 1-3 fluorine atoms or C3-7 cycloalkyls); W2 represents —NR4aC(O)— or the like (where R4a represents a hydrogen atom or C1-6 alkyl group); and ring Q2 represents a C6-10 arylgroup or the like]

IMIDAZO[1,2-A]PYRIDINE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS

The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be u