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Methyl 2-(2-(((benzyloxy)carbonyl)amino)-3-methylpentanamido)acetate is a complex organic compound with the molecular formula C18H26N2O5. It is a derivative of amino acids, featuring a methyl ester group, a benzyloxycarbonyl (Cbz) protecting group, and a 3-methylpentanamido side chain. methyl 2-(2-(((benzyloxy)carbonyl)amino)-3-methylpentanamido)acetate is often used in peptide synthesis as a building block, where the Cbz group serves to protect the amino group during the coupling process, and the methyl ester group allows for easy incorporation into peptide chains. The 3-methylpentanamido side chain provides additional structural diversity and can influence the properties of the resulting peptide. methyl 2-(2-(((benzyloxy)carbonyl)amino)-3-methylpentanamido)acetate is a valuable tool in the field of medicinal chemistry and drug development, particularly for the synthesis of bioactive peptides and proteins.

2280-67-3

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2280-67-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2280-67-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,8 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2280-67:
(6*2)+(5*2)+(4*8)+(3*0)+(2*6)+(1*7)=73
73 % 10 = 3
So 2280-67-3 is a valid CAS Registry Number.

2280-67-3Relevant academic research and scientific papers

Iodine-Mediated Oxidative Coupling of Hydroxamic Acids with Amines towards a New Peptide-Bond Formation

Krishnamurthy, Muniyappa,Vishwanatha,Panguluri, Nageswara Rao,Panduranga,Sureshbabu, Vommina V.

, p. 2565 - 2569 (2015)

An efficient and straightforward approach for the coupling of Nα-protected hydroxamic acids with an amino component in the presence of iodine is delineated. The reaction is mediated by the formation of unstable but reactive acyl nitroso intermediates. The peptide hydroxamic acids were found to be useful substrates in coupling reactions.

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