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BOC-LEU-MET-OME is a peptide compound consisting of four amino acids: leucine (LEU), methionine (MET), and a modified methionine with an omega-methyl group (OME), all protected by a tert-butyloxycarbonyl (BOC) group. This specific sequence and protection scheme are used in peptide synthesis to facilitate the stepwise assembly of larger peptide or protein structures. The BOC group serves as a temporary protecting group for the amino group of the first amino acid in the sequence, preventing unwanted side reactions during the coupling process. Once the peptide bond is formed, the BOC group can be removed to expose the amino group for further reactions, allowing for the addition of subsequent amino acids in the sequence. BOC-LEU-MET-OME is significant in the field of organic chemistry and biochemistry, particularly in the synthesis of pharmaceuticals and the study of protein structure and function.

2280-69-5

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2280-69-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2280-69-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,8 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2280-69:
(6*2)+(5*2)+(4*8)+(3*0)+(2*6)+(1*9)=75
75 % 10 = 5
So 2280-69-5 is a valid CAS Registry Number.

2280-69-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name BOC-LEU-MET-OME

1.2 Other means of identification

Product number -
Other names Boc-L-Leu-L-Leu-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2280-69-5 SDS

2280-69-5Relevant academic research and scientific papers

Design, synthesis, and evaluation of substance P analogue with potential anti-pseudoallergic activity

Wang, Xiangjun,Lu, Jiayu,Zhang, Ting,Ge, Shuai,Lv, Yuexin,Hou, Yajing,Yang, Xinyue,Wang, Cheng,He, Huaizhen

, p. 17584 - 17591 (2021/10/04)

Mast cells (MCs) are innate immune cells that can cause allergic reactions. Pseudo-allergic reactions are a type of reaction that have the clinical symptoms of an allergy without involving the IgE pathway of immune MCs. Some studies have found that the MR

6,Pro9>SP6-11, a Selective Agonist for the Substance P-P-Receptor Subtype

Laufer, Ralph,Gilon, Chaim,Chorev, Michael,Selinger, Zvi

, p. 1284 - 1288 (2007/10/02)

Substitution of a single amino acid residue, proline for glycine-9 in 6>SP6-11, a hexapeptide analogue of substance P, confers on the peptide selective agonist activity toward the SP-P receptor subtype. 6,Prosu

SYNTHESIS OF PENTAPEPTIDES RELATED BOTH TO SUBSTANCE P C-TERMINAL FRAGMENT AND MET-ENKEPHALIN

Lipkowski, Andrzej W.,Misicka, Aleksandra,Drabarek, Stefania

, p. 813 - 818 (2007/10/02)

Six pentapeptide amides related both to Substance P C-terminal fragment and to Met-enkephalin have been synthesized.Syntheses were effected by coupling fragments 3 + 2 in solution.The DCC + HOBt method was used for synthesis of peptide fragments and final

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