73148-99-9Relevant articles and documents
Design, synthesis, and evaluation of substance P analogue with potential anti-pseudoallergic activity
Ge, Shuai,He, Huaizhen,Hou, Yajing,Lu, Jiayu,Lv, Yuexin,Wang, Cheng,Wang, Xiangjun,Yang, Xinyue,Zhang, Ting
, p. 17584 - 17591 (2021/10/04)
Mast cells (MCs) are innate immune cells that can cause allergic reactions. Pseudo-allergic reactions are a type of reaction that have the clinical symptoms of an allergy without involving the IgE pathway of immune MCs. Some studies have found that the MR
Synthesis of substance-P C-terminal hexapeptide analogues and their biological activity. Analogues with antagonistic activity without containing D-amino acids
Karagiannis,Manopoulou,Poulos,Stavropoulos
, p. 667 - 673 (2007/10/02)
Analogues of the C-terminal hexapeptide of substance P have been synthesized in which each amino-acid residue was replaced by the bulky and strong lipophilic residue Asp(OBzl). The amino-acid residue of other selected places has also been replaced by Glu(
Conformationally Restricted C-Terminal Peptides of Substance P. Synthesis, Mass Spectral Analysis and Pharmacological Properties
Theodoropoulos, Dimitrios,Poulos, Constantin,Gatos, Dimitrios,Cordopatis, Pane,Escher, Emanuel,et al.
, p. 1536 - 1539 (2007/10/02)
Four cyclic analogues of the C-terminal hepta- or hexapeptide of substance P were prepared by the solution method.The cyclizations were obtained by substituting with cysteine the residues normally present in positions 5 or 6 or 11 of substance P and by su