22811-14-9Relevant academic research and scientific papers
Facile preparation of 2-imidazolines from aldehydes with tert-butyl hypochlorite
Ishihara, Midori,Togo, Hideo
, p. 1939 - 1942 (2008/02/10)
An efficient and high-yield preparation of 2-imidazolines was achieved from aldehydes and ethylenediamines in the presence of tert-butyl hypochlorite. By this method, 1,3-bis(imidazolin-2-yl)benzene and 2,6-bis(imidazolin-2-yl) pyridine, which act as chiral ligands, could be prepared directly from the corresponding dialdehydes in high yields. Georg Thieme Verlag Stuttgart.
Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites
Carpene,Collon,Remaury,Cordi,Hudson,Nutt,Lafontan
, p. 681 - 688 (2007/10/03)
Nonadrenergic imidazoline binding sites (imidazoline I2 sites) have been described to be colocated with monoamine oxidase (MAO) in the mitochondrial fraction of various cell types. In the present work, the authors considered whether this coloca
Compositions and method comprising heterocyclic compounds containing two heteroatoms
-
, (2008/06/13)
A method and compositions for topically administering physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or formulation for systemic use or to the skin of humans and animals for localized use comprising applying to such skin or membrane a mixture of said physiologically active agent and a non-toxic, effective penetrating amount of penetration enhancing compound having the structural formula I: STR1 wherein: R is a saturated or unsaturated hydrocarbon group with from 5 to 19 carbon atoms; R' and R" are hydrogen, lower alkyl, trifluoromethyl, lower hydroxyalkyl or lower alkyl ester of lower hydroxyalkyl, with the proviso that both R' and R" are not lower hydroxyalkyl; X is O or NR1 ; R1 being hydrogen, lower alkyl, lower alkenyl, lower hydroxyalkyl or lower alkyl ester of lower hydroxyalkyl are disclosed.
