228113-65-3Relevant academic research and scientific papers
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (part 2)
Huang, Horng-Chih,Tremont, Samuel J.,Lee, Len F.,Keller, Bradley T.,Carpenter, Andrew J.,Wang, Ching-Cheng,Banerjee, Shyamal C.,Both, Scott R.,Fletcher, Theresa,Garland, Danny J.,Huang, Wei,Jones, Claude,Koeller, Kevin J.,Kolodziej, Steve A.,Li, James,Manning, Robert E.,Mahoney, Matthew W.,Miller, Raymond E.,Mischke, Deborah A.,Rath, Nigam P.,Reinhard, Emily J.,Tollefson, Michael B.,Vernier, William F.,Wagner, Grace M.,Rapp, Steve R.,Beaudry, Judy,Glenn, Kevin,Regina, Karen,Schuh, Joe R.,Smith, Mark E.,Trivedi, Jay S.,Reitz, David B.
, p. 5853 - 5868 (2007/10/03)
In the preceding paper several compounds were reported as potent apical sodium-codependent bile acid transporter (ASBT) inhibitors. Since the primary site for active bile acid reabsorption is via ASBT, which is localized on the luminal surface of the dist
Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides
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Page column 29, (2010/01/31)
A process for preparing enantiomerically enriched tetrahydrobenzothipeine oxides comprises cyclizing an enantiomerically enriched aryl-3-propanalsulfoxide wherein the sulfur atom of the aryl-3-propanalsulfoxide is a chiral center.
