228120-22-7 Usage
Uses
Used in Pharmaceutical Industry:
1,3,3-TriMethyl-2-[(1E,3E)-3-Methyl-6-(triMethylsilyl)-1,3-hexadien-5-yn-1-yl]-cyclohexene is used as an intermediate in the synthesis of Retinoic Acid derivatives for the pharmaceutical industry. Retinoic Acid, a form of Vitamin A, plays a crucial role in various biological processes, including cell growth, differentiation, and embryonic development. It is also used in the treatment of various skin conditions and has potential applications in cancer therapy.
Used in Chemical Research:
1,3,3-TriMethyl-2-[(1E,3E)-3-Methyl-6-(triMethylsilyl)-1,3-hexadien-5-yn-1-yl]-cyclohexene can also be used in chemical research as a starting material or intermediate for the synthesis of other complex organic compounds. Its unique structure and functional groups make it a valuable component in the development of new chemical entities with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 228120-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,8,1,2 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 228120-22:
(8*2)+(7*2)+(6*8)+(5*1)+(4*2)+(3*0)+(2*2)+(1*2)=97
97 % 10 = 7
So 228120-22-7 is a valid CAS Registry Number.
228120-22-7Relevant academic research and scientific papers
Carboxylate-directed tandem functionalisations of α,β- dihaloalkenoic acids with 1-alkynes: A straightforward access to (Z)-configured, α,β-substituted γ-alkylidenebutenolides
Inack Ngi, Samuel,Cherry, Khalil,Héran, Virginie,Commeiras, Laurent,Parrain, Jean-Luc,Duchêne, Alain,Abarbri, Mohamed,Thibonnet, Jér?me
supporting information; experimental part, p. 13692 - 13696 (2012/01/06)
An easy and mild copper(I)-catalysed lactonisation of readily available (E)-2,3-dihalopropenoic acid derivatives regio- and stereoselectively leads to rarely described (Z)-3-halo-5-ylidene-5H-furan-2-ones. These compounds are subsequently able to undergo classical Pd-catalysed cross-coupling reactions, providing 3-substituted and 3,4-disubstituted 5-ylidene-5H-furan-2-ones (see scheme).
