22817-18-1Relevant academic research and scientific papers
Direct Reduction of Allylic Alcohols Using Isopropanol as Reductant
Sai, Masahiro
, p. 3482 - 3487 (2018)
The lithium cation-catalyzed direct reduction of allylic alcohols to alkenes using isopropanol as a hydride donor was developed. The hydride transfer of the in situ-generated lithium isopropoxide to an allylic cation is the key process in this transformation. The reaction generates only water and acetone as byproducts, which highlights the synthetic utility of this method. (Figure presented.).
Metal-free allylation of electron-rich heteroaryl boronic acids with allylic alcohols
Li, Xue-Dong,Xie, Li-Jun,Kong, De-Long,Liu, Li,Cheng, Liang
, p. 1873 - 1880 (2017/03/10)
A convenient and regioselective cross-coupling of heteroaryl boronic acids with allylic alcohols under catalyst-free reaction conditions is described. The developed procedure is simple, works under external oxidant- and metal-free conditions, and proves to be very general with an unprecedented ortho-selectivity. This approach represents one of the very few examples of ortho-functionalization of boronic acids.
