22821-89-2

Usage

Uses

Used in Pharmaceutical Industry:
1,3-dichloro-5-(methylsulphonyl)benzene is used as an intermediate in the production of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
1,3-dichloro-5-(methylsulphonyl)benzene is utilized as an active ingredient in the manufacture of veterinary drugs and pesticide formulations due to its potent insecticidal and acaricidal properties, which help control pests in agricultural settings.
Used in Chemical Synthesis:
1,3-dichloro-5-(methylsulphonyl)benzene serves as a key intermediate in the synthesis of a range of organic compounds, playing a crucial role in the creation of diverse chemical products.
Used as a Reagent in Chemical Reactions:
In the realm of chemical research and development, 1,3-dichloro-5-(methylsulphonyl)benzene is employed as a reagent to facilitate specific chemical reactions, contributing to the advancement of chemical processes and methodologies.
Caution:
It is imperative to handle 1,3-dichloro-5-(methylsulphonyl)benzene with care due to its toxic nature. It is harmful if swallowed, inhaled, or if it comes into contact with the skin, necessitating proper safety measures during its use and storage.

InChI:InChI=1/C7H6Cl2O2S/c1-12(10,11)7-3-5(8)2-6(9)4-7/h2-4H,1H3

Upstream product

• 68121-46-0 (3,5-dichlorophenyl)(methyl)sulfane 
• 868-85-9 Dimethyl phosphite 
• 5470-49-5 4-methanesulfonylphenylamine 
• 80866-96-2 2,6-dichloro-4-(methylsulfonyl)aniline 

Relevant academic research and scientific papers

High Chemoselectivity in the Construction of Aryl Methyl Sulfones via an Unexpected C-S Bond Formation between Sulfonylhydrazides and Dimethyl Phosphite

A highly chemoselective route to aryl methyl sulfones via an unexpected C S bond formation between sulfonylhydrazides and dimethyl phosphite catalyzed by NaI under mild conditions has been established. This transformation provides an alternative and metal-free pathway to acquire various aryl methyl sulfones in good to excellent yields. Notably, dimethyl phosphite was employed as a stable and readily available alkyl source.

Method for catalytically oxidizing thioether to sulphone

The invention discloses a method for catalytically oxidizing thioether to sulphone. In this method, thioether is added to an ethanol solution. H2 O2 The nitrogen-nitrogen co-doped graphene catalyst is reacted at room temperature to obtain sulfone. The method is simple and convenient to operate, environment-friendly in reaction process, low in production cost, free of metal catalysts, free of secondary pollution, mild in reaction conditions, low in catalyst consumption, high and product yield and the like.

Flow Electrosynthesis of Sulfoxides, Sulfones, and Sulfoximines without Supporting Electrolytes

An efficient electrochemical flow process for the selective oxidation of sulfides to sulfoxides and sulfones and of sulfoxides toN-cyanosulfoximines has been developed. In total, 69 examples of sulfoxides, sulfones, andN-cyanosulfoximines have been synthesized in good to excellent yields and with high current efficiencies. The synthesis was assisted and facilitated through a supporting electrolyte-free, fully automated electrochemical protocol that highlights the advantages of flow electrolysis.

An environmentally benign and selective electrochemical oxidation of sulfides and thiols in a continuous-flow microreactor

A practical and environmentally benign electrochemical oxidation of thioethers and thiols in a commercially-available continuous-flow microreactor is presented. Water is used as the source of oxygen to enable the oxidation process. The oxidation reaction utilizes the same reagents in all scenarios and the selectivity is solely governed by the applied potential. The procedure exhibits a broad scope and good functional group compatibility providing access to various sulfoxides (15 examples), sulfones (15 examples) and disulfides (6 examples). The use of continuous flow allows the optimal reaction parameters (e.g. residence time, applied voltage) to be rapidly assessed, to avoid mass- and heat-transfer limitations and to scale the electrochemistry.