228254-28-2

Upstream product

• 26389-60-6 N-(n-propyl)-N-(cyclopropanemethyl)amine 
• 228254-24-8 3-(2-bromo-4-isopropyl-phenyl)-7-chloro-5-methyl-3H-thiazolo[4,5-d]pyrimidine-2-thione 
• 228254-23-7 4-amino-3-(2-bromo-4-isopropylphenyl)-2-thioxo-2,3-dihydrothiazole-5-carboxamide 
• 246166-33-6 2-bromo-4-isopropylphenylisothiocyanate 
• 51605-97-1 2-bromo-4-isopropylaniline 

Relevant academic research and scientific papers

Thiazolo[4,5-d]pyrimidine thiones and -ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists

A series of thiazolo[4,5-d]pyrimidine thiones and -ones was prepared and discovered to have good binding affinity to the CRH-R1 receptor, thus showing promise as a new class of potential anxiolytics and/or antidepressants.