2283-56-9Relevant academic research and scientific papers
Construction of Sulfonyl Dihydrobenzo[ c]xanthen-7-ones Core via NH4OAc/PdCl2/CuCl2-Mediated Double Cyclocondensation of α-Sulfonyl o-Hydroxyacetophenones with 2-Allylbenzaldehydes
Hsueh, Nai-Chen,Tsai, Min-Chen,Chang, Meng-Yang,Chen, Hsing-Yin
, p. 15915 - 15925 (2019)
NH4OAc/PdCl2/CuCl2 mediated domino double cyclocondensation of α-sulfonyl o-hydroxyacetophenones and 2-allylbenzaldehydes provides tetracyclic sulfonyl dihydrobenzo[c]xanthen-7-one core with good to excellent yields in MeOH. The intermediates contain a 3-sulfonyl flavanone motif. Only water is generated as a byproduct. The use of various catalysts and reaction conditions is studied for the facile-operational conversion.
One-pot access to 2-naphthols and benzofurans via the aerobic Wacker-type oxidation/intramolecular aldol cyclization
Chang, Meng-Yang,Chan, Chieh-Kai,Lin, Shin-Ying
, p. 1532 - 1538 (2013/02/25)
An aerobic Wacker-type oxidation/intramolecular aldol cyclization synthetic route toward two oxygenated 2-naphthols 3 and benzofurans 4 starting with skeleton 2 with good yields is described. The route has been carried by the one-pot transformation of the regioselective PdCl2/CuCl 2-mediated Wacker oxidative cyclization of skeleton 2 with molecular oxygen under the alkaline methanolic condition. Skeleton 2 was prepared from skeleton 1 in moderate total yields via the known protocol.
