22857-30-3

Usage

Uses

Used in Chemical Synthesis:
1-(4-NITRO-PHENYL)-PENTAN-1-ONE is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows it to be a versatile building block for creating a wide range of molecules with different functionalities.
Used in Chemical Reactions:
In the chemical industry, 1-(4-NITRO-PHENYL)-PENTAN-1-ONE is used as a reagent in various chemical reactions. Its reactivity, stemming from the presence of the nitro group, makes it a valuable component in the production of different chemical products.
Used in Pharmaceutical Industry:
1-(4-NITRO-PHENYL)-PENTAN-1-ONE may also find applications in the pharmaceutical industry, where it can be utilized in the development of new drugs or as a reagent in the synthesis of existing medications.
Used in Dye and Pigment Industry:
Due to its yellow color, 1-(4-NITRO-PHENYL)-PENTAN-1-ONE can be used in the dye and pigment industry as a colorant or as a starting material for the production of other colored compounds.
Used in Research and Development:
1-(4-NITRO-PHENYL)-PENTAN-1-ONE is also valuable in research and development settings, where it can be used to study the effects of various functional groups on the properties and reactivity of chemical compounds.

Upstream product

• 38237-74-0 4'-aminopentanophenone 
• 1009-14-9 phenyl butyl ketone 
• 33228-40-9 N-(4-pentanoylphenyl)acetamide 
• 542-69-8 1-iodo-butane 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 61493-21-8 4'-Nitrovalerophenone-O-(2-aminopropyl)oxime hydrochloride 
• 607713-68-8 5-(4-aminophenyl)-6-propylthieno[2,3-d]pyrimidin-4-amine 

Relevant academic research and scientific papers

Regioselective nitration of deactivated mono-substituted benzenes using acyl nitrates over reusable acidic zeolite catalysts

Nitration of benzonitrile was investigated using a nitric acid/acid anhydride/zeolite catalyst system under different reaction conditions. Trifluoroacetic and chloroacetic anhydrides were found to be the most active among the anhydrides tried. Also, zeolites Hβ and Fe3+β (Si/ Al = 12.5) were found to be the most active catalysts. For example, nitration of benzonitrile with trifluoroacetyl nitrate under reflux conditions in dichloromethane gave 3- and 4-nitrobenzonitriles in quantitative yield, of which the para-isomer represented 24-28%. The yield of para-isomer was improved to 33% when passivated Hβ was used under similar reaction conditions. This is easily the most para-selective nitration of benzonitrile ever recorded. Also, no ortho-isomer was formed under the conditions tried. The zeolite can be easily recovered, regenerated by heating and reused up to six times to give results similar to those obtained with a fresh sample of the catalyst. The nitration system was applied successfully to a range of deactivated mono-substituted benzenes to give para-isomers in significantly higher proportions than in the corresponding traditional nitration reactions.

Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors

A series of novel thienopyrimidine-based receptor tyrosine kinase inhibitors has been discovered. Investigation of structure-activity relationships at the 5- and 6-positions of the thienopyrimidine nucleus led to a series of N,N′-diaryl ureas that potentl

Tetraorganogallate complexes in organic chemistry: A novel, efficient and versatile preparation of ketones from acyl chlorides

Tetraorganogallium ate complexes, prepared in situ by addition of an organolithium reagent to a triorganogallium, reacted smoothly with acyl chlorides to yield ketones in high yields and mixed ate complexes display high chemoselectivity in the transfer of one of their ligands.