228572-71-2Relevant articles and documents
Reactions of 1,1,1-trifluoro[chloro]-4-ethoxybut-3-en-2-ones with 1,3- dicarbonyl compounds: Synthesis of 5-acetyl[carboxyethyl]-1,1,1- trifluoro[chloro]hept-3-ene-2,6-diones and their cyclic derivatives phenol, pyridines, and azetone
Zanatta, Nilo,Barichello, Rosemario,Bonacorso, Hello G.,Martins, Marcos A. P.
, p. 765 - 768 (1999)
The synthesis of 5-acetyl[carboxyethyl] 1,1,1-trifluoro[chloro]hept-3- ene-2,6-diones (3a,b, 4a,b) and their cyclic derivatives 1-[2-hydroxy-4- (trifluoromethyl)phenyl]ethanone (5a), 1-[2-hydroxy-6- (trichloro[fluoro]methyl)pyridin-3-yl]ethanone (6c, 7c), and 3-acetylazet- 2(1H)-one (8), obtained from the reactions of 1,1,1-trifluoro[chloro]-4- ethoxybut-3-en-2-one (1, 2), with 1,3-dicarbonyl compounds such as acetylacetone (a), ethyl acetoacetate (b), and acetoacetamide (c) and sodium hydride in anhydrous THF, is reported.