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59938-07-7

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59938-07-7 Usage

General Description

(E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one, also known as trichloroethoxybutenone, is a chemical compound with a molecular formula C6H7Cl3O2. It is an organic compound that consists of a trichloromethyl group and an ethoxy group attached to a butenone backbone. (E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one is primarily used in the synthesis of pharmaceuticals and as a chemical intermediate in organic synthesis. It is also used as a reagent in chemical reactions and as a building block for the preparation of other organic compounds. Trichloroethoxybutenone is a highly reactive compound and should be handled with care due to its potential hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 59938-07-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,9,3 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 59938-07:
(7*5)+(6*9)+(5*9)+(4*3)+(3*8)+(2*0)+(1*7)=177
177 % 10 = 7
So 59938-07-7 is a valid CAS Registry Number.

59938-07-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-1,1,1-trichloro-4-ethoxy-3-buten-2-one

1.2 Other means of identification

Product number -
Other names 1,1,1-Trichloro-4-ethoxy-but-3-en-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:59938-07-7 SDS

59938-07-7Relevant articles and documents

TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE

-

Paragraph 1156; 1157, (2021/02/12)

The present disclosure relates to bifunctional compounds, which find utility as modulators of tan protein. In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a VHL or cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds tan protein, such that tan protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of tan. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of tan protein. Diseases or disorders that result from aggregation or accumulation of tan protein are treated or prevented with compounds and compositions of the present disclosure.

Br?nsted Acid Catalyzed Tandem Defunctionalization of Biorenewable Ferulic acid and Derivates into Bio-Catechol

Bal, Mathias,Bomon, Jeroen,Liao, Yuhe,Maes, Bert U. W.,Sels, Bert F.,Sergeyev, Sergey,Van Den Broeck, Elias,Van Speybroeck, Veronique

supporting information, p. 3063 - 3068 (2020/02/05)

An efficient conversion of biorenewable ferulic acid into bio-catechol has been developed. The transformation comprises two consecutive defunctionalizations of the substrate, that is, C?O (demethylation) and C?C (de-2-carboxyvinylation) bond cleavage, occurring in one step. The process only requires heating of ferulic acid with HCl (or H2SO4) as catalyst in pressurized hot water (250 °C, 50 bar N2). The versatility is shown on a variety of other (biorenewable) substrates yielding up to 84 % di- (catechol, resorcinol, hydroquinone) and trihydroxybenzenes (pyrogallol, hydroxyquinol), in most cases just requiring simple extraction as work-up.

Synthesis and RT inhibitory activity evaluation of new pyrimidine-based Seco-nucleosides

Vargas, Genaro,Escalona, Iker,Salas, Magali,Gordillo, Barbara,Sierra, Adolfo

, p. 243 - 257 (2007/10/03)

Eleven new 3 ′,4 ′- seco acyclic nucleosides (4-14) were prepared by nucleophilic substitution of protected pyrimidine bases on ethyl 3,3-diethoxypropanoate (3). Structures were characterized spectroscopically and a brief analysis of their conformation in solution was performed by the vicinal coupling constants 3 J H 2′ aH 3′ and 3 J H 2′ bH 3′. In solid state, compound 6 forms a homodimer linked by hydrogen bonding. In preliminary tests all compounds show low toxicity and gentle activity against HIV-1 RT in vitro. Copyright Taylor & Francis Group, LLC.

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