22862-75-5

Usage

Uses

Used in Pharmaceutical Industry:
(2S,3R,4R)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate hydrochloride (1:1) is used as a potential drug or precursor for drug synthesis due to its unique structure and stereochemistry. The presence of the hydroxyl, acetate, and methoxybenzyl groups, along with the hydrochloride salt, may contribute to its medicinal properties and formulation in pharmaceutical products.
Used in Research Applications:
(2S,3R,4R)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate hydrochloride (1:1) may be utilized in research settings for studying its potential biological activities and interactions with biological targets. The hydrochloride salt form of the compound could be particularly useful in experiments involving the compound's solubility and reactivity in various conditions.

Upstream product

• 180081-83-8 (2R,3S,4S)-3-Acetoxy-1-(tert-butoxycarbonyl)-4-(tert-butyldimethylsilyloxy)-2-(4-methoxybenzyl)pyrrolidine 
• 865814-24-0 tert-butyl (2S,3R,4R)-3-(acetyloxy)-4-{[(tert-butoxy)carbonyl]oxy}-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate 
• 249617-04-7 Benzyl-[(1R,2S)-2-benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(4-methoxy-benzyl)-ethyl]-amine 
• 186465-29-2 (2S,3S,4R)-4-(Benzylamino)-3-(benzyloxy)-5-(4-methoxyphenyl)pentane-1,2-diol 
• 186465-39-4 (2R,3S,4S)-1-Benzyl-3-(benzyloxy)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine 
• 400009-32-7 (2R,3S,4S)-1-benzyl-4-benzyloxy-3-hydroxy-2-(4-methoxybenzyl)pyrrolidine 
• 865814-10-4 tert-butyl (2R,3S,4S)-3-(acetyloxy)-4-{[(tert-butoxy)carbonyl]oxy}-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate 
• 400009-33-8 (2R,3S,4S)-3-acetoxy-1-benzyl-4-benzyloxy-2-(4-methoxybenzyl)pyrrolidine 

Relevant academic research and scientific papers

Stereoselective Total Synthesis of Unnatural (+)-Anisomycin

Stereoselective total synthesis of unnatural (+)-anisomycin from d-glucose has been achieved with an overall yield of 23%. The key synthetic features are regioselective opening of an epoxide, azidation of the resulting alcohol, and finally one-pot hydroge

Syntheses of enantiomerically pure 2-substituted pyrrolidin-3-ones via lithiated alkoxyallenes - An auxiliary-based synthesis of both enantiomers of the antibiotic anisomycin

The hydrochlorides of both enantiomers of the antibiotic anisomycin were prepared starting with the 'diacetone-fructose'-substituted allene 1 and the N-Boc-protected imine precursor 2a. Addition of an excess of lithiated 1 to 2a provided a 2:1 mixture 3a

An aldol-based approach to the synthesis of the antibiotic anisomycin

Chemical equation presented A new approach to the synthesis of the antibiotic anisomycin is reported that relies upon a key aldol disconnection. The glycolate aldol coupling proceeds in 75% yield and with >95% diastereoselectivity, which allows the 13-step synthesis to proceed in 35% overall yield.

Stereoselective synthesis and biological evaluation of anisomycin and 2- substituted analogues

The naturally occurring pyrrolidine anisomycin 1, its deacetyl derivative 9k, and some previously unknown analogues were prepared from 2-O- benzyl-3,4-O-isopropylidene-L-threose 2, via the N-benzylimine 3, using highly threo-selective additions of organol