228704-07-2

Basic information

• Product Name: N-Tsoc-phenylalanine methyl ester
• Synonyms: N-Tsoc-phenylalanine methyl ester
• CAS NO: 228704-07-2
• Molecular Weight: 379.572
• Mol File: 228704-07-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-Tsoc-phenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Tsoc-phenylalanine methyl ester(228704-07-2)
• EPA Substance Registry System: N-Tsoc-phenylalanine methyl ester(228704-07-2)

Safety Data

• Hazardous Substances Data: 228704-07-2(Hazardous Substances Data)

Upstream product

• 6485-79-6 chlorotriisopropylsilane 
• 124-38-9 carbon dioxide 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 

Downstream Products

• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 

Relevant articles and documents

Catalytic dehydrogenative N-((triisopropylsilyl)oxy)carbonyl (Tsoc) protection of amines using iPr3SiH and CO2

A versatile method has been found to catalyze the dehydrogenative N-((triisopropylsilyl)oxy)carbonyl (Tsoc) protection of amines using Pd/C, volatile iPr3SiH and CO2 gas without the liberation of any salts. A simple filtration/evaporation process facilitates the easy isolation of the product, thereby enhancing the utility of Tsoc as an amine-protecting group in organic synthesis.