228725-37-9

Upstream product

• 228728-08-3 6-Iodo-8-fluoro-4-hydroxy-3-quinolinecarboxylic acid ethyl ester 
• 104-86-9 4-chlorobenzylamine 
• 29632-74-4 2-fluro-4-iodoaniline 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 228728-67-4 3-{[(4-Chlorobenzyl)amino]-carbonyl}-8-fluoro-4-hydroxy-6-quinolinecarboxylic acid 
• 228725-83-5 N-[(4-chlorophenyl)methyl]-6-cyano-8-fluoro-4-hydroxy-3-quinoline-carboxamide 
• 228725-85-7 N-[(4-chlorophenyl)methyl]-8-fluoro-4-hydroxy-6-(3-hydroxy-1-propynyl)-3-quinolinecarboxamide 
• 228726-50-9 N-[(4-chlorophenyl)methyl]-8-fluoro-4-hydroxy-6-[3-(methylthio)-1-propynyl]-3-quinolinecarboxamide 
• 228726-78-1 N-(4-chlorobenzyl)-8-fluoro-4-hydroxy-6-[(E)-3-oxo-1-butenyl]-3-quinolinecarboxamide 
• 228726-75-8 3-(3-{[(4-chlorobenzyl)amino]carbonyl}-8-fluoro-4-hydroxy-6-quinolinyl)-2-propynyl phenylcarbamate 
• 228726-41-8 N-(4-Chlorobenzyl)-4-hydroxy-6-iodo-8-methoxy-3-quinolinecarboxamide 
• 228726-68-9 N-(4-chlorobenzyl)-8-fluoro-6-(3-fluoro-1-propynyl)-4-hydroxy-3-quinolinecarboxamide 
• 228726-33-8 methyl 3-(((4-Chlorobenzyl)amino)carbonyl)-8-fluoro-4-hydroxy-6-quinolinecarboxylate 
• 1224582-34-6 C₂₄H₁₆ClFN₂O₃S 

Relevant academic research and scientific papers

The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase

Discovery efforts were focused on identifying a non-nucleoside antiviral for treating infections caused by human cytomegalovirus (HCMV) with equal or better potency and diminished toxicity compared to current therapeutics. This Letter describes the HCMV D

4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS

The present invention provides 4-hydroxyquinoline-3-carboxamide and hydrazide compounds of formula I These compounds are useful to treat or prevent the herpesviral infections, particularly, human cytomegaloviral infection.

Oxazinoquinolones useful for the treatment of viral infections

The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.

Quinolinecarboxamides as antiviral agents

The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.

4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents

The present invention provides 4-hydroxyquinoline-3-carboxamide and hydrazide compounds of formula I These compounds are useful to treat or prevent the herpesviral infections, particularly, human cytomegaloviral infection.