228864-26-4Relevant academic research and scientific papers
A novel synthesis of 1,3-benzodiazepin-2-ones using intramolecular heck reaction
Hayashi, Masahito,Sai, Hiroshi,Horikawa, Hiroshi
, p. 1331 - 1335 (1998)
The formation of the skeleton of 1,3-benzodiazepin-2-one could be efficiently achieved by intramolecular Heck reaction. This methodology was well applicable to the preparation of optically pure 4-substituted 1,3-benzodiazepin-2-ones starting from easily available α-amino acids.
