228868-08-4Relevant academic research and scientific papers
Synthesis of new chiral peptide nucleic acid (PNA) monomers by a simplified reductive amination method
Falkiewicz, Bogdan,Kowalska, Katarzyna,Kolodziejczyk, Aleksandra S.,Wisniewski, Kazimierz,Lankiewicz, Leszek
, p. 353 - 361 (2007/10/03)
The aim of this work was the preparation of four new peptide nucleic acid (PNA) monomer backbone by reductive amination of N(α)-Boc-protected chiral amino aldehydes, derived from Leu, Phe, Tyr(Bzl), and Thr(Bzl), with methyl glycinate. To the crude 2-subs
