22892-67-7

Upstream product

• 106-96-7 propargyl bromide 
• 932-90-1 Benzaldoxime 
• 100-52-7 benzaldehyde 

Downstream Products

• 20056-75-1 N-benzyl-O-prop-2-ynyl-hydroxylamine 
• 326622-05-3 N-allyl-N-benzyl-O-prop-2-ynyl-hydroxylamine 

Relevant academic research and scientific papers

The design, synthesis and biological evaluation of novel thiamin diphosphate analog inhibitors against the pyruvate dehydrogenase multienzyme complex E1 from Escherichia coli

Pyruvate dehydrogenase multienzyme complex E1 (PDHc E1) is a potential target enzyme when looking for inhibitors to combat microbial disease. In this study, we designed and synthesized a series of novel thiamin diphosphate (ThDP) analogs with triazole rin

With bactericidal activity of 2 - methyl - 4 - amino - 5 - (substituted - 1, 2, 3 - triazolyl) methyl pyrimidine derivatives, preparation method and application thereof

The invention discloses 2-methyl-4-amino-5-(substituted-1,2,3-triazolyl)methylpyridine derivatives having a bactericidal activity, and a preparation method and an application thereof, wherein the derivatives have the structural formula described in the specification, wherein R represents H or I, X represents O, NH or S, Y represents benzoylamide thiocarbonyl or substituted benzoylamide thiocarbonyl, 2-phenyl-1,3,4-thiadiazole(oxadiazole)-5-yl or 2-substituted phenyl-1,3,4-thiadiazole(oxadiazole)-5-yl, benzophenone (acetophenone) imine or substituted benzophenone (acetophenone) imine, and Y-involved substituents on a benzene ring mainly comprise H, halogen, nitro, cyano group, CF3, C1-4 alkyl, methoxyl, C1-2 carboxylic group or carboxylate group. The compounds have a significant control effect on wheat gibberellic hypha, rice rhizoctonia solani, cucumber borrytis cinerea, tomato alternaria solani, alternaria alternata and cucumber colletrichum orbiculare, and can be used for bactericidal active ingredients.

Synthesis of 3,4-substituted cyclopentenones via an intramolecular Pauson-Khand reaction of N-O linked enynes

Differentially 3,4-disubstituted cyclopentenones are constructed via a novel Pauson-Khand cyclization/cleavage strategy of N-O linked enynes. (C) 2000 Published by Elsevier Science Ltd.