22892-77-9Relevant academic research and scientific papers
Nickel-Catalyzed Transformation of Alkene-Tethered Oxime Ethers to Nitriles by a Traceless Directing Group Strategy
Takahashi, Yoshiyuki,Tsuji, Hiroaki,Kawatsura, Motoi
, p. 2654 - 2665 (2020/02/04)
Nickel-catalyzed transformation of alkene-tethered oxime ethers to nitriles using a traceless directing group strategy has been developed. A series of alkene-tethered oxime ethers derived from benzaldehyde and cinnamyl aldehyde derivatives were converted into the corresponding benzonitriles and cinnamonitriles in 46-98% yields using the nickel catalyst system. Control experiments showed that the alkene group tethered to an oxygen atom on the oximes via one methylene unit plays a key role as a traceless directing group during the catalysis.
Oxime ether containing active group and synthesis method thereof
-
Paragraph 0049-0053; 0057-0059, (2020/01/04)
The invention relates to the technical field of organic matter synthesis, in particular to oxime ether containing an active group and a synthesis method thereof, and the oxime ether has a structure asshown in a general formula (I) which is described in th
A three-component approach to isoquinoline derivatives by cycloaddition/Heck reaction sequence
Oikawa, Masato,Takeda, Yoshiyuki,Naito, Shinya,Hashizume, Daisuke,Koshino, Hiroyuki,Sasaki, Makoto
, p. 4255 - 4258 (2008/02/08)
Here, we report a three-component coupling reaction approach between an aldehyde, an allyloxyamine, and a maleimide toward isoquinoline derivatives. At first, an oxime O-allylic ether, prepared by dehydrative condensation of the aldehyde and the allyloxya
Tandem oxidation processes: The direct conversion of activated alcohols into oximes; synthesis of citaldoxime
Kanno, Hisashi,Taylor, Richard J. K.
, p. 1287 - 1290 (2007/10/03)
The direct conversion of primary alcohols into oximes is reported using manganese dioxide and alkoxylamines/hydroxylamine as their hydrochloride salts or supported on Amberlyst 15. This transformation has been applied to a range of benzylic, allylic and propargylic alcohols and utilised to prepare the natural product citaldoxime.
