229022-43-9Relevant academic research and scientific papers
Synthesis of highly substituted 1,3-dienes and 1,3,5-trienes by the palladium-catalyzed coupling of vinylic halides, internal alkynes, and organoboranes
Zhang, Xiaoxia,Larock, Richard C.
, p. 2993 - 2996 (2003)
(Matrix presented) Highly substituted 1,3-dienes and trienes have been prepared in good to excellent yields by the palladium-catalyzed coupling of vinylic halides, internal alkynes, and organoboranes.
A Pd NP-confined novel covalent organic polymer for catalytic applications
Yadav, Deepika,Awasthi, Satish Kumar
, p. 1320 - 1325 (2020/02/04)
A novel unsymmetrical covalent organic polymer, COP (1), was designed and characterized using several analytical and spectroscopic techniques. COP (1) was synthesized via the nucleophilic substitution reaction of 2,4,6-trichloro-1,3,5-triazine with p-amin
Controlled Single and Double Iodofluorination of Alkynes with DIH- and HF-Based Reagents
Pfeifer, Lukas,Gouverneur, Véronique
supporting information, p. 1576 - 1579 (2018/03/23)
A novel protocol for the regio- and stereoselective iodofluorination of internal and terminal alkynes using 1,3-diiodo-5,5,-dimethylhydantoin and HF-based reagents is disclosed. This approach is used to prepare a fluorinated tamoxifen derivative in two steps from commercially available starting materials. A facile method enabling controlled regioselective double iodofluorination of terminal alkynes is also presented.
Cross-coupling reactions using porous multipod Cu2O microcrystals as recoverable catalyst in aqueous media
Tang, Lin,Wu, Chaoting,Hu, Qiyan,Li, Qian,Zhang, Wu
, (2017/09/06)
Porous multipod Cu2O microcrystals were found to be an efficient, highly recyclable and eco-friendly catalyst for the cross-coupling reactions of aryl halides and terminal alkynes with high yields in aqueous media. Noteworthy, the Cu2O catalyst can be reused for several times without significant decrease in catalytic activity.
A phosphine-free, atom-efficient cross-coupling of aryl iodides with triarylindiums or trialkynylindiums catalyzed by immobilization of palladium(0) in MCM-41
Lei, Zhiwei,Liu, Haiyi,Cai, Mingzhong
, p. 54 - 63 (2017/10/25)
The first phosphine-free heterogeneous atom-efficient cross-coupling reaction of aryl iodides with triarylindiums or trialkynylindiums was achieved in THF at 68 °C by using 1 mol% of MCM-41-immobilized palladium(0)-Schiff base complex [MCM-41-N,N-Pd(0)] as catalyst, yielding a variety of unsymmetrical biaryls and arylalkynes in good to excellent yields. The heterogeneous palladium(0) catalyst could easily be prepared via a simple procedure from commercially readily available reagents, and recovered by filtration of the reaction solution and recycled at least 10 times without significant loss of activity.
Tetraalkynylstannanes in the Stille cross coupling reaction: a new effective approach to arylalkynes
Levashov, Andrey S.,Buryi, Dmitrii S.,Goncharova, Olga V.,Konshin, Valeriy V.,Dotsenko, Victor V.,Andreev, Alexey A.
, p. 2910 - 2918 (2017/04/14)
The Stille-type cross coupling reaction with tetraalkynylstannanes was studied in detail for the first time. The reaction provides a simple and effective route towards a variety of arylalkynes. The advantages and limitations of the proposed procedure are discussed.
Palladium-free and phosphine-free Sonogashira coupling reaction of aryl halides with terminal alkynes catalyzed by boehmite nanoparticle-anchored Cu(I) diethylenetriamine complex
Bakherad, Mohammad,Doosti, Rahele,Mirzaee, Mahdi,Jadidi, Khosrow,Amin, Amir H.,Amiri, Omid
, p. 7347 - 7363 (2017/10/06)
In this work, a novel diethylenetriamine-functionalized-boehmite nanoparticle-supported Cu(I) catalyst is synthesized. The catalyst prepared is then characterized by FT-IR spectroscopy, scanning electron microscopy, transmission electron microscopy, X-ray
An ambient temperature Sonogashira cross-coupling protocol using 4-aminobenzoic acid as promoter under copper and amine free conditions
Das, Sameeran Kumar,Sarmah, Manashi,Bora, Utpal
, p. 2094 - 2097 (2017/05/10)
A new methodology has been developed based on Pd(OAc)2 and 4-aminobenzoic acid catalytic system for the Sonogashira cross-coupling reaction at ambient temperature under copper and amine free conditions. The newly developed catalytic system is conveniently applicable to the aryl iodides and terminal acetylenes. The catalytic system is much efficient because of the use of easily available and low cost additive.
A coordination driven self-assembled Pd6L8 nanoball catalyses copper and phosphine-free Sonogashira coupling reaction in both homogeneous and heterogeneous formats
Pradhan, Subhashis,Dutta, Subhadip,John, Rohith P.
, p. 7140 - 7147 (2016/08/10)
A Pd6L8 type coordination driven self-assembly was constructed using a tripodal ligand L (L = N1,N3,N5-trimethyl-N1,N3,N5-tris[(pyridin-4-yl)methyl]-1,3,5-benzene tric
Highly Regio and Stereoselective Intermolecular Seleno- and Thioamination of Alkynes
Zheng, Guangfan,Zhao, Jinbo,Li, Zhanyu,Zhang, Qiao,Sun, Jiaqiong,Sun, Haizhu,Zhang, Qian
supporting information, p. 3513 - 3518 (2016/03/05)
By using N-fluorobenzenesulfonimide as both the oxidant and the amination reagent, we have realized the first example of the intermolecular chalcogenative amination of alkynes, which grants facile, highly regio- and stereoselective access to chalcogenated enamides. The reaction features mild conditions, high yields and selectivities, remarkably broad substrate scope, and excellent functional group tolerance. Mechanistic studies indicate the in situ generated chalcogen imidates to be the actual reactive species, which in turn, has clarified the mechanism of related transformations. These reactions represent significant additions to the development of the highly selective amino bisfunctionalization of alkynes.
