229031-94-1Relevant academic research and scientific papers
Rearrangement of epoxides in non-aldol aldol process: Allylic vs. tertiary and secondary carbocationic centers
Jung, Michael E.,Marquez, Rodolfo
, p. 3129 - 3132 (1999)
It has been shown that allylic carbocations are formed in preference to tertiary or secondary carbocations in the rearrangement of substituted epoxides. However protection of the alkene as a bromo ether allows for the desired rearrangement and production of intermediates for the synthesis of the cytotoxic tedanolides.
