22907-68-2Relevant academic research and scientific papers
Compositions and methods of the use thereof achiral analogues of CC-1065 and the duocarmycins
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, (2008/06/13)
The present invention relates to novel achiral seco-analogues of the DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II III, IV and V: wherein X is a good leaving group, such as a chl
Compositions and methods of the use thereof achiral analogues of CC-1065 and the duocarmycins
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Page column 35, (2010/02/05)
The present invention relates to novel achiral seco-analogues of DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II, III, IV and V: wherein X is a good leaving group, such as a chlori
SYNTHESIS AND DNA BINDING PROPERTIES OF A PURINE ANALOGUE OF BISBENZIMIDE
Lee, Moses,Spotts, P. Hunter,Eckert, Jeffrey,Walker, Clint,Nobles, Jennifer A.
, p. 2093 - 2097 (2007/10/02)
The synthesis of a purine containing analogue (1) of bisbenzimide (2) and its DNA binding properties are described.Analogue 1 is found to have increased tolerance for binding to GC sites implying the formation of the new hydrogen bonds between guanine-2-N
