229162-10-1Relevant academic research and scientific papers
Synthesis of novel analogues of the delta opioid ligand SNC-80 using REM resin
Cottney,Rankovic,Morphy
, p. 1323 - 1328 (1999)
Focused libraries of delta opioid ligands were synthesised using REM resin methodology. Several high affinity compounds were identified with good selectivity over the g opioid receptor. Automated REM resin recycling was used to synthesise larger amounts o
Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis
Barn,Bom,Cottney,Caulfield,Morphy
, p. 1329 - 1334 (1999)
Two focused libraries of delta opioid ligands were synthesised using AlCl3 facilitated aminolysis. Several compounds were identified with DOR binding affinities higher or similar to SNC-80. A novel acyclic derivative of SNC-80 produced antinoci
