22927-13-5

Basic information

• Product Name: 2-ETHYLBENZALDEHYDE
• Synonyms: 2-ethyl-benzaldehyd;Benzaldehyde, 2-ethyl-;6-Ethyl benzaldehyde;o-Ethylbenzaldehyde
• CAS NO: 22927-13-5
• Molecular Formula: C₉H₁₀O
• Molecular Weight: 134.18
• Product Categories: Benzaldehyde;Aldehydes;C9;Carbonyl Compounds;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 22927-13-5.mol

Chemical Properties

• Melting Point: 210 °C
• Boiling Point: 212 °C(lit.)
• Flash Point: 230 °F
• Appearance: /
• Density: 1.02 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.2mmHg at 25°C
• Refractive Index: n20/D 1.538(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-ETHYLBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYLBENZALDEHYDE(22927-13-5)
• EPA Substance Registry System: 2-ETHYLBENZALDEHYDE(22927-13-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 22927-13-5(Hazardous Substances Data)

Usage

Uses

Used in Animal-derived Food Products:
2-Ethylbenzaldehyde is used as a flavoring agent in the animal-derived food products industry, adding a unique and pleasant aroma to these products.
Used in Pharmaceutical Industry:
2-Ethylbenzaldehyde is used as a reactant for the preparation of potential antibacterial agents, contributing to the development of new drugs to combat bacterial infections.
Used in Chemical Synthesis:
2-Ethylbenzaldehyde is used as a reactant in asymmetric addition reactions, which are crucial for the synthesis of various complex organic molecules with specific stereochemistry.
Used in Dye Industry:
2-Ethylbenzaldehyde is used as a reactant in the solid-phase synthesis of BODIPY dyes, which are widely used in various applications, including fluorescence imaging and sensing.
Used in Sensor Development:
2-Ethylbenzaldehyde is used in the development of an Ig fluorescent sensor, which can be employed in the detection and analysis of specific biomolecules.
Used in Nanotechnology:
2-Ethylbenzaldehyde is used in condensation reactions with phenylenediamine or aminothiophenol, catalyzed by mesoporous mixed metal oxide nanocrystals prepared from the aerogel process. This application is significant in the field of nanotechnology, where these nanocrystals can be utilized in various applications, such as catalysis and sensing.

InChI:InChI=1/C9H10O/c1-2-8-5-3-4-6-9(8)7-10/h3-7H,2H2,1H3

Upstream product

• 119391-23-0 C₁₆H₁₇N₂O₃S^(1-)*Na⁽¹⁺⁾ 
• 1973-22-4 1-bromo-2-ethylbenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 97-94-9 triethyl borane 
• 84761-77-3 2-formylphenyl triflate 
• 496-11-7 INDANE 
• 76118-05-3 2-ethylbenzoyl chloride 
• 767-90-8 (2-ethylphenyl)methanol 
• 28272-96-0 2-vinylbenzaldehyde 
• 611-14-3 2-Ethyltoluene 
• 201230-82-2 carbon monoxide 
• 18282-40-1 1-ethyl-2-iodobenzene 
• 38846-64-9 2-ethynylbenzaldehyde 
• 21450-63-5 2-ethylphenylmagnesium bromide 

Downstream Products

• 90672-03-0 (2-Ethyl-phenyl)-(3-methyl-isothiazol-5-yl)-methanol 
• 103988-23-4 3-(2-ethyl-phenyl)-acrylic acid 
• 1310480-69-3 C₁₉H₁₉N 
• 1310480-64-8 1-(2-ethylbenzyl)-3,3-dimethyl-1-(naphthalen-1-yl)urea 
• 1310480-67-1 C₁₉H₁₇N 
• 7564-63-8 2-ethylstyrene 
• 854664-97-4 3-(2-ethylphenyl)propan-1-ol 
• 129075-84-9 3-(2-ethylphenyl)propanoic acid 

Relevant articles and documents

Chromium(VI) supported and entrapped on silica and zirconia as recyclable materials for oxidation of alcohols

Oxidation of alcohols have been realized with Cr(VI) oxide supported or entrapped, via sol-gel methodology, on silica and zirconia. These materials were easily recovered from the reaction mixture without leaching of chromium in solution. Moreover, recycling studies have indicated that they can be regenerated by calcinations at 400-600°C or by treatment with ozone at room temperature. In the case of Cr(VI) entrapped into silica matrix up to 18 oxidation cycles have been realized without loss in activity.

Cooperative Catalysis for Selective Alcohol Oxidation with Molecular Oxygen

The activation of dioxygen for selective oxidation of organic molecules is a major catalytic challenge. Inspired by the activity of nitrogen-doped carbons in electrocatalytic oxygen reduction, we combined such a carbon with metal-oxide catalysts to yield

Radical induced disproportionation of alcohols assisted by iodide under acidic conditions

The disproportionation of alcohols without an additional reductant and oxidant to simultaneously form alkanes and aldehydes/ketones represents an atom-economical transformation. However, only limited methodologies have been reported, and they suffer from a narrow substrate scope or harsh reaction conditions. Herein, we report that alcohol disproportionation can proceed with high efficiency catalyzed by iodide under acidic conditions. This method exhibits high functional group tolerance including aryl alcohol derivatives with both electron-withdrawing and electron-donating groups, furan ring alcohol derivatives, allyl alcohol derivatives, and dihydric alcohols. Under the optimized reaction conditions, a 49% yield of 5-methyl furfural and a 49% yield of 2,5-diformylfuran were obtained simultaneously from 5-hydroxymethylfurfural. An initial mechanistic study suggested that the hydrogen transfer during this redox disproportionation occurred through the inter-transformation of HI and I2. Radical intermediates were involved during this reaction.

6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to antiviral agents. Specifically, the present invention relates to compounds of formula I which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

NOVEL 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for mating the compounds.

NOVEL OXALYL PIPERAZINES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

NOVEL INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

NOVEL, HIGHLY ACTIVE PYRAZOLO-PIPERIDINE SUBSTITUTED INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

NOVEL, HIGHLY ACTIVE AMINO-THIAZOLE SUBSTITUTED INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

Synthesis of Tetrahydroisoquinolines by Visible-Light-Mediated 6- exo -trig Cyclization of α-Aminoalkyl Radicals

Starting from the respective tertiary α-silylmethyl amines, the intramolecular cyclization of α-aminoalkyl radicals to Michael acceptors produced tetrahydroisoquinolines. The reaction conditions included the use of 5 molpercent of an iridium photoredox catalyst, dimethylformamide as the solvent, and equimolar amounts of water and cesium carbonate as the additives. 13 substrates were synthesized from ortho -alkylbenzaldehydes in a three-step procedure involving a carbonyl condensation, a radical bromination, and a substitution by a secondary α-silylmethyl amine. After optimization of the photocyclization, the reaction delivered tetrahydroisoquinolines in moderate to high yields (41-83percent). A facial diastereoselectivity (dr ? 80:20) was observed with chiral substrates and a crystal structure provided evidence for the relative configuration of the major diastereoisomer. A catalytic cycle with direct electron transfer to the photoexcited metal catalyst is proposed.