229486-45-7Relevant academic research and scientific papers
Reaction of α-bromolevoglucosenone with 2,2-disubstituted 1,3-dinitropropanes
Faizullina,Iskakova,Pershin,Salikhov,Safarov,Valeev
, p. 456 - 459 (2012)
2,2-Bis(nitromethyl)decane and 4-methyl-2,2-bis(nitromethyl)pentane reacted with α-bromolevoglucosenone in the presence of a base under ultrasonic treatment to give the corresponding cyclopenta-fused derivatives. Analogous reactions of 1,1-bis(nitromethyl
Ketones as electrophile in nitroaldol reaction: Synthesis of β,β-disubstituted-1,3-dinitroalkanes and allylic nitro compounds
Costa, Jeronimo S.,Gomes, Alex O.,Pereira, Vera Lúcia P.,de Souza, Douglas L. F.
, p. 1575 - 1583 (2021/07/06)
β,β-Disubstituted-1,3-dinitro compounds were obtained exclusively with an overall yield of 83% through a domino nitroaldol/elimination/1,4-addition process, when excess nitromethane was added to cyclohexanone or butanone using DBU (1,8-diazabicyclo[5.4.0]
Methylcarbonate and bicarbonate phosphonium salts as catalysts for the nitroaldol (Henry) reaction
Fabris, Massimo,Noe, Marco,Perosa, Alvise,Selva, Maurizio,Ballini, Roberto
experimental part, p. 1805 - 1811 (2012/04/17)
Phosphonium ionic liquids exchanged with bicarbonate and methylcarbonate anions (CILs) exhibit catalytic performances comparable to those of sterically hindered (non nucleophilic) organosuperbases such as DBU. At 25-50 °C, under solventless conditions, CI
P(RNCH2CH2)3N: An Efficient Promoter for the Nitroaldol (Henry) Reaction
Kisanga, Philip B.,Verkade, John G.
, p. 4298 - 4303 (2007/10/03)
The use of catalytic amounts of the proazaphosphatranes P(MeNCH2CH2)3N, P(i-PrNCH2CH2)3N and P(HNCH2CH2)(i-PrNCH2CH2) 2N as nonionic bases in the reaction of nitroalkanes with carbonyl compounds is reported. The reaction proceeds at room temperature in the presence of 2.2 equiv of magnesium sulfate to produce the corresponding β-nitroalkanols in generally superior yields. Aldehydes react quantitatively in 5-60 min, whereas ketones require up to 3 h to react with nitromethane and up to 7 h for the reaction of ketones with higher nitroalkanes.
