2296-53-9 Usage
Uses
Used in Pharmaceutical Industry:
2,2,2-Trichloro-1-(piperidin-1-yl)ethanone is used as a synthetic intermediate for the development of pharmaceuticals. Its unique structure, featuring a carbonyl group and a piperidine ring, allows for the creation of a wide range of bioactive compounds with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 2,2,2-trichloro-1-(piperidin-1-yl)ethanone serves as a versatile intermediate. The presence of the three chlorine atoms in the molecule contributes to its reactivity, facilitating various chemical reactions and processes, and enabling the synthesis of a diverse array of organic compounds.
Overall, 2,2,2-trichloro-1-(piperidin-1-yl)ethanone is a valuable chemical compound with important applications in both the pharmaceutical industry and organic synthesis, owing to its unique structure and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 2296-53-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,9 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2296-53:
(6*2)+(5*2)+(4*9)+(3*6)+(2*5)+(1*3)=89
89 % 10 = 9
So 2296-53-9 is a valid CAS Registry Number.
2296-53-9Relevant academic research and scientific papers
Formation of N-Substituted Trichloroacetamides from Amines and Hexachloroacetone
Bew, Clive,Joshi, Virginia Otero de,Gray, Jim,Kaye, Perry T.,Meakins, G. Denis
, p. 945 - 948 (2007/10/02)
Procedures are described for converting primary amines into their well-crystalline trichloroacetyl-derivatives by treatment with hexachloroacetone under mild conditions.Although secondary aromatic N-methylamines are unaffected by hexachloroacetone, saturated heterocyclic amines react vigorously.A mechanistic study using 2-amino-4-t-butylthiazole showed that the reaction is first order in hexachloroacetone, second order in amine, and base-catalysed; there is no appreciable kinetic isotope (H/D) effect nor accumulation of intermediates during the reaction.A sequence which accommodates these results is suggested.
