229623-53-4 Usage
Description
1,2-Benzisoxazole-6-carbonitrile,3-amino-(9CI) is a chemical compound characterized by the molecular formula C9H6N2O. It is a derivative of benzisoxazole, featuring a carbonitrile and an amino group within its structure. 1,2-Benzisoxazole-6-carbonitrile,3-amino-(9CI) is recognized for its potential as a building block in the synthesis of biologically active molecules, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1,2-Benzisoxazole-6-carbonitrile,3-amino-(9CI) is utilized as a key intermediate in the production of pharmaceuticals due to its unique structure and the presence of an amino group, which allows for the creation of a variety of biologically active molecules. Its versatility in synthesis contributes to the development of new drugs and therapeutic agents.
Used in Agrochemicals:
In the agrochemical sector, 1,2-Benzisoxazole-6-carbonitrile,3-amino-(9CI) serves as a valuable intermediate for the synthesis of compounds with pesticidal or herbicidal properties, leveraging its chemical reactivity and structural attributes to enhance crop protection solutions.
Used in Fine Chemicals:
1,2-Benzisoxazole-6-carbonitrile,3-amino-(9CI) also finds application in the synthesis of fine chemicals, where its specific functional groups can be exploited to produce specialty chemicals for various industrial applications, including but not limited to fragrances, dyes, and other high-value products.
Used in Drug Discovery and Medicinal Chemistry Research:
1,2-Benzisoxazole-6-carbonitrile,3-amino-(9CI) holds promise for further research and development in drug discovery and medicinal chemistry, given its potential to be modified and optimized for specific therapeutic targets, thus contributing to the advancement of novel treatment options.
Check Digit Verification of cas no
The CAS Registry Mumber 229623-53-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,9,6,2 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 229623-53:
(8*2)+(7*2)+(6*9)+(5*6)+(4*2)+(3*3)+(2*5)+(1*3)=144
144 % 10 = 4
So 229623-53-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H5N3O/c9-4-5-1-2-6-7(3-5)12-11-8(6)10/h1-3H,(H2,10,11)
229623-53-4Relevant articles and documents
PYRIDINES AND PYRIDINE N-OXIDES AS MODULATORS OF THROMBIN
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Page/Page column 27, (2010/11/28)
The present invention describes compounds of Formula I: wherein W, X, Y, Z, and Q are defined herein, or a pharmaceutically acceptable salt thereof, for the prophylaxis, or treatment of diseases and conditions related to thrombin activity in a mammal.
Non-covalent thrombin inhibitors featuring P3-heterocycles with P1-bicyclic arginine surrogates
Cui, Jingrong Jean,Araldi, Gian-Luca,Reiner, John E.,Reddy, Komandla Malla,Kemp, Scott J.,Ho, Jonathan Z.,Siev, Daniel V.,Mamedova, Lala,Gibson, Tony S.,Gaudette, John A.,Minami, Nathaniel K.,Anderson, Susanne M.,Bradbury, Annette E.,Nolan, Thomas G.,Semple
, p. 2925 - 2930 (2007/10/03)
Novel, potent, and highly selective classes of thrombin inhibitors were identified, which resulted from judicious combination of P4-aromatics and P2-P3-heterocyclic dipeptide surrogates with weakly basic (calcd pKa ～non-basic - 8.6) bicyclic P1-arginine mimics. The design, synthesis, and biological activity of achiral, non-covalent, orally bioavailable inhibitors NC1-NC44 featuring P1-indazoles, benzimidazoles, indoles, benzotriazoles, and aminobenzisoxazoles is disclosed.
