229640-28-2Relevant academic research and scientific papers
Arylmethanesulfonates are convenient latent phenols in the nucleophilic aromatic substitution reaction
Dinsmore, Christopher J.,Zartman, C. Blair
, p. 3989 - 3990 (1999)
The methanesulfonyl protecting group for a phenol is conveniently unmasked under the conditions of the S(N)Ar reaction with an activated aryl halide, producing diarylether products directly. The method is advantageous when the preparation of a phenol substrate requires O-protection, since the selection of the robust methanesulfonate as a latent phenol obviates a deprotection step prior to the S(N)Ar reaction.
