22978-42-3

Basic information

• Product Name: Benzamide, N-phenyl-2-(trifluoromethyl)-
• Synonyms: 2-trifluoromethylbenzoic acid anilide;Benzamide, N-phenyl-2-(trifluoromethyl)-;2-trifluoromethylbenzanilide;2-Trifluormethylbenzanilid
• CAS NO: 22978-42-3
• Molecular Formula: C14H10F3NO
• Molecular Weight: 265.235
• Mol File: 22978-42-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 151-152 °C
• Boiling Point: 274.7±40.0 °C(Predicted)
• Density: 1.314±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzamide, N-phenyl-2-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-phenyl-2-(trifluoromethyl)-(22978-42-3)
• EPA Substance Registry System: Benzamide, N-phenyl-2-(trifluoromethyl)-(22978-42-3)

Safety Data

• Hazardous Substances Data: 22978-42-3(Hazardous Substances Data)

Upstream product

• 362694-31-3 N-(2-iodophenyl)-2-(trifluoromethyl)benzamide 
• 392-83-6 o-trifluoromethylphenyl bromide 
• 103-71-9 phenyl isocyanate 
• 425415-37-8 N-(2-bromophenyl)-2-trifluoromethylbenzamide 
• 201230-82-2 carbon monoxide 
• 444-29-1 2-iodo(trifluoromethyl)benzene 
• 62-53-3 aniline 
• 591-50-4 iodobenzene 
• 360-64-5 2-(trifluoromethyl)benzamide 
• 312-94-7 2-trifluoromethylbenzoyl chloride 

Downstream Products

• 67679-24-7 CF₃C₆H₄C(O)N(SCCl₂CFCl₂)C₆H₅ 
• 64922-34-5 N-(fluorodichloromethylthio)-2-trifluoromethylbenzanilide 

Relevant articles and documents

Exploration of Cu-catalyzed regioselective hydrodehalogenation of o-haloanilides using EtOH as hydrogen source

In present work, we have explored a Cu(acac)2/vasicine-catalyzed regioselective hydrodehalogenation methodology of o-haloanilides using EtOH as hydrogen source and solvent. The catalytic system could selectively dehalogenate 2-Br and 2-I, and features regioselective, efficient and functional group tolerance.

Efficient Pd-Catalyzed Hydrodehalogenation of o -Haloanilides in Water

In the present work, we have developed a practical methodology for the hydrodehalogenation of o -haloanilides using PdCl 2at 100 °C under mild conditions in water. The catalytic system could selectively dehalogenate both aryl chloride and aryl bromide and exhibit a broad functional group tolerance.

Experimental and computational insights into the nature of weak intermolecular interactions in trifluoromethyl-substituted isomeric crystalline N-methyl-N-phenylbenzamides

The knowledge about the prevalence of weak interactions in terms of the nature and energetics associated with their formation is of significance in organic solids. In the present study, we have systematically explored the existence of different types of i