22988-52-9 Usage
General Description
4-(5-methyl-2-thienyl)-4-oxobutyric acid is a chemical compound that belongs to the family of thienyl-oxobutyric acids. 4-(5-METHYL-2-THIENYL)-4-OXOBUTYRIC ACID is characterized by its molecular structure consisting of a thienyl group, a methyl group, and a ketone group, along with a carboxylic acid functional group. It is used in the pharmaceutical industry for the synthesis of various drugs and pharmaceuticals due to its potential biological activities. Additionally, it has been studied for its potential role in the treatment of various diseases and disorders, including neurological and psychiatric conditions. Overall, 4-(5-methyl-2-thienyl)-4-oxobutyric acid is a versatile chemical with potential applications in medicine and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 22988-52-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,9,8 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 22988-52:
(7*2)+(6*2)+(5*9)+(4*8)+(3*8)+(2*5)+(1*2)=139
139 % 10 = 9
So 22988-52-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O3S/c1-6-2-4-8(13-6)7(10)3-5-9(11)12/h2,4H,3,5H2,1H3,(H,11,12)
22988-52-9Relevant articles and documents
ARYLAMIDES AND METHODS OF USE THEREOF
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Page/Page column 94-95, (2021/06/11)
The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.
Peculiarities of the behavior of succinyl dichloride in Friedel-Crafts reaction with thiophenes
Smirnov,Afanas'Ev,Belen'kii
scheme or table, p. 1199 - 1207 (2011/10/13)
The reactions of thiophene, 2-methyl-, and 2-bromothiophene with succinyl dichloride in the presence of AlCl3, TiCl4, and SnCl 4 have been studied. The effect of the acylation conditions, the relative amounts and nature of the Lewis acid on the ratio and yields of the 1,4-di(2-thienyl)-1,4-diones and 4-oxo-4-(2-thienyl)butyric acids formed have been demonstrated. Under the reaction conditions, the formation of 4,4-di(2-thienyl)but-3-enoic acids (the main products in many cases) and also 4,4-di(2-thienyl)-butyrolactones was demonstrated.
