229961-22-2

Basic information

• Product Name: Benzoic acid, 4-[(3,4-dihydro-2,2-dimethyl-4-oxo-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester
• CAS NO: 229961-22-2
• Molecular Formula: C22H20O3S
• Molecular Weight: 364.465
• Mol File: 229961-22-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[(3,4-dihydro-2,2-dimethyl-4-oxo-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[(3,4-dihydro-2,2-dimethyl-4-oxo-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester(229961-22-2)
• EPA Substance Registry System: Benzoic acid, 4-[(3,4-dihydro-2,2-dimethyl-4-oxo-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester(229961-22-2)

Safety Data

• Hazardous Substances Data: 229961-22-2(Hazardous Substances Data)

Upstream product

• 111424-51-2 6-methoxy-2,2-dimethyl-thiochroman-4-one 
• 111424-46-5 3-(4-methoxy-phenylsulfanyl)-3-methyl-butyric acid 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 229961-91-5 6-ethynyl-2,2,-dimethylthiochroman-4-one 
• 619-58-9 4-iodobenzoic acid 
• 60-29-7 diethyl ether 
• 229961-88-0 6-hydroxy-2,2-dimethyl-thiochroman-4-one 
• 541-47-9 3-Methylbutenoic acid 
• 696-63-9 4-Methoxybenzenethiol 
• 229961-89-1 2,2-dimethyl-4-oxo-thiochroman-6-yl trifluoromethanesulfonate 
• 229961-90-4 2,2-dimethyl-6-trimethylsilanyl-ethynyl-thiochroman-4-one 

Downstream Products

• 229961-23-3 ethyl 4-((2,2-dimethyl-4-trifluorosulfonyloxy-(2H)-thiochromen-6-yl)ethynyl)-benzoate 
• 229961-29-9 ethyl 4-<<4-(4-tert-butylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-32-4 ethyl 4-<<4-(5-tert-butyl-thiophen-2-yl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-28-8 ethyl 4-<<4-(4-isopropylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-27-7 ethyl 4-<<4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-31-3 ethyl 4-<<4-(5-ethyl-thiophen-2-yl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-26-6 ethyl 4-<<4-(4-methylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-45-9 VTP 194310 
• 229961-33-5 ethyl 4-<<4-(6-methyl-pyridin-3-yl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-30-2 ethyl 4-<<4-(5-methyl-thiophen-2-yl)-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 
• 229961-24-4 ethyl 4-<<4-phenyl-2,2-dimethyl-(2H)-thiochromen-6-yl>ethynyl>-benzoate 

Relevant articles and documents

EXPANSION OF RENEWABLE STEM CELL POPULATIONS

Ex vivo and in vivo methods of expansion of renewable stem cells, expanded populations of renewable stem cells and their uses.

Methods of treatment during vascular procedures

The invention provides in one embodiment a method for treating vascular trauma. The method can include administering to an individual undergoing vascular trauma an effective amount of a retinoic acid receptor (RAR) antagonist or an RAR inhibitor. The meth

SYNTHESIS AND USE OF RETINOID COMPOUNDS HAVING NEGATIVE HORMONE AND/OR ANTAGONIST ACTIVITIES

2,2-Dialkyl-4-aryl-substituted benzopyran and benzothiopyran derivatives of the formula STR1 where the symbols have the meaning described in the specification, have retinoid negative hormone and/or antagonist-like biological activities. The invented RAR antagonists can be administered to mammals, including humans, for the purpose of preventing or diminishing action of RAR agonists on the bound receptor sites. Specifically, the RAR agonists are administered or coadministered with retinoid drugs to prevent or ameliorate toxicity or side effects caused by retinoids or vitamin A or vitamin A precursors. The retinoid negative hormones can be used to potentiate the activities of other retinoids and nuclear receptor agonists.