229980-47-6Relevant academic research and scientific papers
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity
Porcelli,Gilardi,Laghezza,Piemontese,Mitro,Azzariti,Altieri,Cervoni,Fracchiolla,Giudici,Guerrini,Lavecchia,Montanari,Di Giovanni,Paradiso,Pochetti,Simone,Tortorella,Crestani,Loiodice
experimental part, p. 37 - 54 (2012/03/09)
A series of ureidofibrate-like derivatives was prepared and assayed for their PPAR functional activity. A calorimetric approach was used to characterize PPARγ-ligand interactions, and docking experiments and X-ray studies were performed to explain the obs
MORPHOLINE COMPOUND
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Page/Page column 114, (2010/11/27)
A compound represented by the formula (1) wherein ring A is aryl optionally having substituent(s) and the like; ring B is arylene optionally having substituent(s) and the like; m=0-2; n=1-5; X is a bond and the like; Y is a bond and the like; and Z is hydrogen atom and the like or a pharmaceutically acceptable salt thereof, and a hydrate or solvate thereof have affinity for CCR3, and can be pharmaceutical products for the treatment and/or prophylaxis of immune or inflammatory diseases.
INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION
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, (2010/02/15)
There is provided a compound of formula: (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
