229982-34-7Relevant academic research and scientific papers
Enantioselective Deuteration of β-Substituted α,β-Unsaturated Esters by Rhodium-1,2-Bis(2,5-diphenylphospholano)ethane
Lethu, Sébastien,Ano, Hikaru,Murata, Michio,Matsuoka, Shigeru
, p. 235 - 239 (2018)
We report an efficient method for the synthesis of a chiral C-CHD-CHD-C unit in threo form, which enables the asymmetric conformational analysis of straight alkyl chains. The vicinal dideuterated compound was constructed by enantioselective catalytic deut
Total synthesis of (+)-pilosinine via a stereodivergent conjugate addition strategy
Schrank, Cassandra L.,Danneman, Michael W.,Prebihalo, Emily A.,Anderson, Robert E.,Gibson, Tyler J.,Wuest, William M.,Mullins, Richard J.
supporting information, (2020/04/27)
In recent work, asymmetric conjugate addition reactions to chiral 4-phenyl-N-enoyl-1,3-oxazolidinones have been shown to give different stereochemical outcomes depending on the conditions employed. Through the application of stereodivergent reaction conditions, the total synthesis of (+)-pilosinine and the formal synthesis of (?)-pilosinine has been completed from a single enantiomer of the 1,3-oxazolidinone auxiliary.
2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION
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, (2008/06/13)
The present invention has its object to provide a 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine derivative represented with the Formula (1) , or the pharmaceutically acceptable salt, which is effective as a therapeutic and prophylactic agent for diabetes, diabetic nephropathy, or glomerulosclerosis.
2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION
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Page/Page column 52, (2010/11/30)
A 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine derivative represented by the generalformula (1): [Chemical formula 1] (1) or a pharmaceutically acceptable saltthereof. They are useful as a therapeutic/preventive agent for diabetes, diabeticnephropathy, or glomerulosclerosis.
