23000-37-5Relevant academic research and scientific papers
AROMATIC COMPOUNDS FOR USE IN ACTIVATING HEMATOPOIETIC STEM AND PROGENITOR CELLS
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Page/Page column 101-102, (2020/06/19)
Disclosed herein are new aromatic compounds, compositions that include one or more aromatic compounds, and methods of synthesizing the same. Also disclosed herein are methods of increasing and/or expanding cells, including stem cells, hematopoietic stem cells, progenitor cells, and placenta or cord blood-derived cells, with one or more compounds or compositions described herein. Also disclosed herein are methods of increasing and/or expanding differentiated hematopoietic cells with one or more compounds or compositions described herein.
Inhibitors of ketohexokinase: Discovery of pyrimidinopyrimidines with specific substitution that complements the ATP-binding site
Maryanoff, Bruce E.,O'Neill, John C.,McComsey, David F.,Yabut, Stephen C.,Luci, Diane K.,Jordan Jr., Alfonzo D.,Masucci, John A.,Jones, William J.,Abad, Marta C.,Gibbs, Alan C.,Petrounia, Ioanna
supporting information; experimental part, p. 538 - 543 (2011/09/15)
Attenuation of fructose metabolism by the inhibition of ketohexokinase (KHK; fructokinase) should reduce body weight, free fatty acids, and triglycerides, thereby offering a novel approach to treat diabetes and obesity in response to modern diets. We have
