23009-01-0

Basic information

• Product Name: 2-Oxazolidinone, 3-methyl-5-[4-(4-phenyl-1-piperazinyl)butyl]-
• CAS NO: 23009-01-0
• Molecular Formula: C18H27N3O2
• Molecular Weight: 317.431
• Mol File: 23009-01-0.mol

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-methyl-5-[4-(4-phenyl-1-piperazinyl)butyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-methyl-5-[4-(4-phenyl-1-piperazinyl)butyl]-(23009-01-0)
• EPA Substance Registry System: 2-Oxazolidinone, 3-methyl-5-[4-(4-phenyl-1-piperazinyl)butyl]-(23009-01-0)

Safety Data

• Hazardous Substances Data: 23009-01-0(Hazardous Substances Data)

Upstream product

• 23109-29-7 3-methyl-5-(4-chlorobutyl)-2-oxazolidinone 
• 92-54-6 4-phenyl-1-piperazine 
• 7179-96-6 N-methyl-1-(tetrahydro-2H-pyran-2-yl)methanamine 
• 108-20-3 di-isopropyl ether 
• 4004-95-9 1-phenylpiperazine hydrochloride 

Relevant articles and documents

Series of 5-[-(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone derivatives useful in the treatment of allergic conditions

A method of treating allergic disorders and pharmaceutical compositions therefore are disclosed for a series of 5-[(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone derivatives of Formula I. These compounds are useful in inhibiting Type I allergic STR1 responses in a living animal and thus can be used to treat allergic phenomena such as asthma, rhinitis, atopic dermatitis, chronic hives, allergic conjunctivitis and the like.

METHOD OF TREATING ANXIETY WITH 5-[(4-ARYL OR HETEROARYL-1-PIPERAZINYL)ALKYL]-2-OXAZOLIDINONES

This invention discloses the antianxiety properties of compounds of the formula: STR1 wherein n is 3 or 4, R is C 1-C. sub.4 alkyl or phenyl, and Ar is STR2 where Z is selected from H, C. sub.1-C 4 alkoxy, C 2-C 4 alkenyloxy or hydroxy.